LongevityMap Gene

Gene details

HGNC symbol
ANKRD24 
Aliases
 
Common name
ankyrin repeat domain 24 
Description
Cytogenetic Location
19p13.3
UCSC Genome Browser
View 19p13.3 on the UCSC genome browser
OMIM
Ensembl
ENSG00000089847
UniProt/Swiss-Prot
ANR24_HUMAN
Entrez Gene
170961
UniGene
197872
1000 Genomes
1000 Genomes

Homologs in model organisms

Danio rerio
ankrd24
Mus musculus
Ankrd24
Rattus norvegicus
uncharacterized_D3Z9

Studies (1)

Significant/Non-significant: 0/1

Longevity Association
Non-significant
Population
Italian (Southern)
Study Design
A two-stage case-control study was performed to identify the association between longevity and variation of in homeostasis regulation pathway genes. 317 SNPs in 104 genes were analyzed in 78 cases (≥90 years, median age 98 years, 42 females) and 71 controls (<90 years, median age 67 years, 32 females) in stage 1. Then, 31 candidate SNPs identified in stage 1 (π markers = 0.1) were analyzed in an independent sample composed by 288 cases (≥90 years, median age 92 years, 163 females) and 554 controls (<90 years, median age 67 years, 277 females).
Conclusions
After adjustment for multiple testing, no significant association was identified between various SNPs and longevity.
Indentifier
rs352496
Reference