LongevityMap Gene

Gene details

HGNC symbol
ACSS3 
Aliases
 
Common name
acyl-CoA synthetase short-chain family member 3 
Description
Cytogenetic Location
12q21.31
UCSC Genome Browser
View 12q21.31 on the UCSC genome browser
OMIM
614356
Ensembl
ENSG00000111058
UniProt/Swiss-Prot
A0A0B4J1R2_HUMAN
Entrez Gene
79611
UniGene
259559
1000 Genomes
1000 Genomes

Homologs in model organisms

Danio rerio
acss3
Drosophila melanogaster
CG6432
Mus musculus
Acss3
Rattus norvegicus
Acss3

Studies (1)

Significant/Non-significant: 0/1

Longevity Association
Non-significant
Population
American (Caucasian)
Study Design
Genome-wide association study for longevity-related traits in up to 1345 Framingham Study participants from 330 families; 713 participants achieved age 65 years or greater. A total of 79 potential candidate genes and regions associated with longevity were also studied.
Conclusions
Although no genome-wide associations were significant, mutiple SNPs and genes had suggestive associations with both age at death and morbidity-free survival at age 65 years
Indentifier
rs10506274
Reference