Flachsbart et al. (2009)
- Longevity Association
- Study Design
- 16 known FOXO3A SNPs were examined in 1,762 German centenarians/nonagenarians and younger controls
- Polymorphisms in FOXO3A were associated with longevity. The FOXO3A association was considerably stronger in centenarians than in nonagenarians, highlighting the importance of centenarians for genetic longevity research. Replication in 535 French centenarians (mean age: 103.8 years) and 553 younger controls (aged 18–70 years) generated a trend that supported the results, although it was not statistically significant.
Other variants which are also part of this study