LongevityMap variant

Entry Details

Longevity Association
Significant
Population
German
Study Design
16 known FOXO3A SNPs were examined in 1,762 German centenarians/nonagenarians and younger controls
Conclusions
Polymorphisms in FOXO3A were associated with longevity. The FOXO3A association was considerably stronger in centenarians than in nonagenarians, highlighting the importance of centenarians for genetic longevity research. Replication in 535 French centenarians (mean age: 103.8 years) and 553 younger controls (aged 18–70 years) generated a trend that supported the results, although it was not statistically significant.
Identifier
rs479744
In Other Studies (IDs)
1992
Cytogenetic Location
6q21
UCSC Genome Browser
View 6q21 on the UCSC genome browser

References

Flachsbart et al. (2009)

Other variants which are also part of this study