Human Ageing Genomic Resources

The Human Ageing Genomic Resources (HAGR) is a collection of databases and tools designed to help researchers understand the genetics of human ageing through a combination of functional genomics and evolutionary biology. A major resource in HAGR is GenAge, which includes a curated database of genes related to human ageing and a database of ageing- and longevity-associated genes in model organisms. To search for ageing-related genes:

Another major database in HAGR is AnAge. Featuring over 4,000 species, AnAge provides a compilation of data on ageing, longevity, and life history that is ideal for the comparative biology of ageing. To search for a particular species or taxon:

We also develop computational tools. In particular, we maintain a Perl toolkit, the Ageing Research Computational Tools (ARCT), that includes data-mining and phylogenetic analysis algorithms, tools to access external databases, sequence and transcription factor analysis tools, etc. Also featured is a method that allows researchers to determine the rate of ageing of a given population from demographic parameters. Please visit our software section.

Other projects currently in development include evolutionary studies and gene expression analyses.

If you are interested in the genomics of ageing, please spare a moment to read our scientific strategy. In case you are lost, you can always visit our help section or search our resources. You can also learn more about our project and the people responsible, and please remember to read our disclaimer and copyright. Usage of HAGR or any of its associated resources implies you have read, understood, and accepted our terms and conditions and will abide by them.

Lastly, we have an extensive list of links regarding computational biology, genomics, gerontology, and comparative biology.

Feedback on all aspects of HAGR is always appreciated. To receive the latest news and announcements concerning HAGR, please join the HAGR-news mailing list.