Ageing-Associated Genes in Model Organisms

Found 877 results. Showing results 401 to 600.

Entrez ID Symbol Name Organism Longevity influence Max average lifespan change More details
172099 htp-3 Him-Three Paralog Caenorhabditis elegans Anti-Longevity 19% Increase htp-3
171939 hus-1 human HUS1 related Caenorhabditis elegans Anti-Longevity 11% Increase hus-1
177660 hyl-1 Homolog of Yeast Longevity gene Caenorhabditis elegans Pro-Longevity 10% Decrease hyl-1
177775 idh-1 Protein IDH-1 Caenorhabditis elegans Anti-Longevity Increase idh-1
172655 idha-1 Protein IDHA-1 Caenorhabditis elegans Anti-Longevity Increase idha-1
181699 ifa-3 Intermediate filament protein ifa-3 Caenorhabditis elegans Anti-Longevity Increase ifa-3
187585 ifd-1 Intermediate filament protein ifd-1 Caenorhabditis elegans Anti-Longevity Increase ifd-1
176755 ife-1 Initiation Factor 4E (eIF4E) family Caenorhabditis elegans Anti-Longevity Increase ife-1
180393 ife-2 Initiation Factor 4E (eIF4E) family Caenorhabditis elegans Anti-Longevity Increase ife-2
176373 iff-1 Initiation Factor Five (eIF-5A) homologs Caenorhabditis elegans Anti-Longevity Increase iff-1
174322 ifg-1 Initiation Factor 4G (eIF4G) family Caenorhabditis elegans Anti-Longevity 55% Increase ifg-1
181182 ifp-1 Intermediate filament protein ifp-1 Caenorhabditis elegans Anti-Longevity Increase ifp-1
189055 ifta-2 IntraFlagellar Transport Associated Caenorhabditis elegans Anti-Longevity 50% Increase ifta-2
172584 iftb-1 eIFTwoBeta (eIF2beta translation initiation factor) Caenorhabditis elegans Anti-Longevity Increase iftb-1
173001 impt-1 Protein IMPACT homolog Caenorhabditis elegans Anti-Longevity 16% Increase impt-1
175966 inf-1 INitiation Factor Caenorhabditis elegans Unclear Increase and Decrease inf-1
177936 ins-1 INSulin related Caenorhabditis elegans Pro-Longevity 25% Increase ins-1
172600 ins-18 INSulin related Caenorhabditis elegans Anti-Longevity Increase ins-18
191689 ins-21 INSulin related Caenorhabditis elegans Anti-Longevity Increase ins-21
191688 ins-7 INSulin related Caenorhabditis elegans Anti-Longevity 12% Increase ins-7
172488 inx-14 INneXin Caenorhabditis elegans Anti-Longevity Increase inx-14
178101 inx-8 INneXin Caenorhabditis elegans Anti-Longevity 19% Increase inx-8
191694 inx-9 INneXin Caenorhabditis elegans Anti-Longevity 28% Increase inx-9
174305 ire-1 IRE1 kinase related Caenorhabditis elegans Pro-Longevity 20% Decrease ire-1
177609 isp-1 Iron-Sulfur Protein Caenorhabditis elegans Anti-Longevity 60% Increase isp-1
177546 itr-1 Inositol Triphosphate Receptor Caenorhabditis elegans Pro-Longevity 53% Increase itr-1
180810 jkk-1 JNK Kinase Caenorhabditis elegans Unannotated Decrease jkk-1
175080 jmjd-2 Lysine-specific demethylase 4 Caenorhabditis elegans Anti-Longevity 13% Increase jmjd-2
177460 jnk-1 Jun N-terminal Kinase Caenorhabditis elegans Pro-Longevity Increase and Decrease jnk-1
186841 K01C8.7 Protein K01C8.7 Caenorhabditis elegans Anti-Longevity 20% Increase K01C8.7
177624 K07H8.1 Protein K07H8.1 Caenorhabditis elegans Anti-Longevity Increase K07H8.1
187128 K07H8.8 Protein K07H8.8 Caenorhabditis elegans Anti-Longevity 22% Increase K07H8.8
176814 K08E3.5 Protein K08E3.5 Caenorhabditis elegans Anti-Longevity Increase K08E3.5
173397 K10B4.3 Protein K10B4.3 Caenorhabditis elegans Anti-Longevity Increase K10B4.3
173349 K11B4.1 Protein K11B4.1 Caenorhabditis elegans Anti-Longevity 16% Increase K11B4.1
178892 K11D12.9 Protein K11D12.9 Caenorhabditis elegans Pro-Longevity Decrease K11D12.9
187337 K12H4.5 Protein K12H4.5 Caenorhabditis elegans Anti-Longevity 58% Increase K12H4.5
174161 kat-1 3-Ketoacyl-coA Thiolase Caenorhabditis elegans Pro-Longevity 30% Decrease kat-1
175404 klf-1 Kruppel-Like Factor (zinc finger protein) Caenorhabditis elegans Pro-Longevity 15% Increase klf-1
177557 klo-1 hypothetical protein Caenorhabditis elegans Pro-Longevity 15% Decrease klo-1
184000 klo-2 hypothetical protein Caenorhabditis elegans Pro-Longevity 15% Decrease klo-2
191275 kri-1 human KRIT 1 (Krev interaction trapped/cerebral cavernous malformation 1) homolog Caenorhabditis elegans Pro-Longevity Decrease kri-1
189370 lagr-1 LAG1 (yeast Longevity-Assurance Gene) Related Caenorhabditis elegans Pro-Longevity 10% Decrease lagr-1
172499 lars-2 Leucyl Amino-acyl tRNA Synthetase Caenorhabditis elegans Anti-Longevity Increase lars-2
179161 lbp-4 Lipid Binding Protein Caenorhabditis elegans Pro-Longevity Decrease lbp-4
172390 lbp-6 Lipid Binding Protein Caenorhabditis elegans Unclear Increase and Decrease lbp-6
191701 lbp-7 Lipid Binding Protein Caenorhabditis elegans Anti-Longevity Increase lbp-7
188761 lbp-8 Lipid Binding Protein Caenorhabditis elegans Pro-Longevity 30% Increase lbp-8
178686 lbp-9 Lipid Binding Protein Caenorhabditis elegans Pro-Longevity Decrease lbp-9
181292 ldb-1 LIM domain Binding Protein Caenorhabditis elegans Pro-Longevity Decrease ldb-1
175058 lem-2 LEM domain protein Caenorhabditis elegans Pro-Longevity Decrease lem-2
174462 let-23 LEThal Caenorhabditis elegans Pro-Longevity Increase and Decrease let-23
172167 let-363 LEThal Caenorhabditis elegans Anti-Longevity 150% Increase let-363
178970 let-418 Protein let-418 Caenorhabditis elegans Anti-Longevity 25% Increase let-418
172088 let-502 LEThal Caenorhabditis elegans Pro-Longevity 30% Decrease let-502
178104 let-60 LEThal Caenorhabditis elegans Unannotated Increase let-60
172153 let-630 hypothetical protein Caenorhabditis elegans Anti-Longevity 18% Increase let-630
178120 let-653 LEThal Caenorhabditis elegans Pro-Longevity 13% Decrease let-653
175934 let-765 LEThal Caenorhabditis elegans Pro-Longevity 27% Decrease let-765
179854 letm-1 LETM1 (Leucine zipper, EF-hand, TransMembrane mitochondrial protein) homolog Caenorhabditis elegans Anti-Longevity 21% Increase letm-1
174050 lgg-1 LC3, GABARAP and GATE-16 family Caenorhabditis elegans Pro-Longevity 43% Decrease lgg-1
172893 lin-11 Protein LIN-11 Caenorhabditis elegans Pro-Longevity 9% Decrease lin-11
181337 lin-14 abnormal cell LINeage Caenorhabditis elegans Anti-Longevity 31% Increase lin-14
181662 lin-15B abnormal cell LINeage Caenorhabditis elegans Pro-Longevity 42% Decrease lin-15B
181400 lin-2 abnormal cell LINeage Caenorhabditis elegans Unclear Increase lin-2
174058 lin-23 abnormal cell LINeage Caenorhabditis elegans Pro-Longevity Decrease lin-23
172626 lin-28 Protein lin-28 Caenorhabditis elegans Anti-Longevity 20% Increase lin-28
178001 lin-3 abnormal cell LINeage Caenorhabditis elegans Pro-Longevity Decrease lin-3
266860 lin-4 abnormal cell LINeage Caenorhabditis elegans Pro-Longevity lin-4
178788 lin-40 abnormal cell LINeage Caenorhabditis elegans Pro-Longevity Increase and Decrease lin-40
174267 lin-5 Protein LIN-5 Caenorhabditis elegans Anti-Longevity 16% Increase lin-5
171739 lin-65 hypothetical protein Caenorhabditis elegans Pro-Longevity 24% Decrease lin-65
191704 lip-1 Lateral-signal-Induced Phosphatase Caenorhabditis elegans Anti-Longevity 8% Increase lip-1
179046 lipl-4 LIPase Like Caenorhabditis elegans Pro-Longevity 55% Increase lipl-4
172687 lmn-1 nuclear LaMiN Caenorhabditis elegans Pro-Longevity 12% Decrease lmn-1
172037 lpd-5 LiPid Depleted Caenorhabditis elegans Anti-Longevity 17% Increase lpd-5
179477 lpd-9 LiPid Depleted Caenorhabditis elegans Anti-Longevity 10% Increase lpd-9
181297 lpr-5 Protein LPR-5 Caenorhabditis elegans Pro-Longevity 16% Decrease lpr-5
177988 lsm-7 LSM Sm-like protein Caenorhabditis elegans Pro-Longevity 24% Decrease lsm-7
184622 lys-10 LYSozyme Caenorhabditis elegans Anti-Longevity 20% Increase lys-10
178087 lys-6 LYSozyme Caenorhabditis elegans Anti-Longevity 13% Increase lys-6
173944 lys-8 LYSozyme Caenorhabditis elegans Pro-Longevity 29% Decrease lys-8
187451 M05B5.2 Protein M05B5.2 Caenorhabditis elegans Pro-Longevity 45% Decrease M05B5.2
177113 M57.2 Protein M57.2 Caenorhabditis elegans Pro-Longevity 20% Decrease M57.2
173073 mag-1 Drosophila MAGonashi homolog Caenorhabditis elegans Pro-Longevity 15% Decrease mag-1
174181 maoc-1 MAO-C-like dehydratase domain Caenorhabditis elegans Anti-Longevity Increase maoc-1
178089 mars-1 Methionyl tRNA Synthetase Caenorhabditis elegans Anti-Longevity 23% Increase mars-1
179794 max-1 Motor AXon guidance Caenorhabditis elegans Anti-Longevity Increase max-1
3565400 max-2 Motor AXon guidance Caenorhabditis elegans Anti-Longevity 25% Increase max-2
181681 mboa-1 Protein MBOA-1 Caenorhabditis elegans Pro-Longevity 16% Decrease mboa-1
174841 mcm-2 yeast MCM (licensing factor) related Caenorhabditis elegans Unclear Increase and Decrease mcm-2
179041 mdh-1 Malate DeHydrogenase Caenorhabditis elegans Anti-Longevity 4% Increase mdh-1
175936 mdh-2 Malate DeHydrogenase Caenorhabditis elegans Pro-Longevity 10% Decrease mdh-2
180942 mdl-1 MAD-Like Caenorhabditis elegans Anti-Longevity 16% Increase mdl-1
175817 mdt-15 Mediator of RNA polymerase II transcription subunit 15 Caenorhabditis elegans Pro-Longevity 34% Decrease mdt-15
173960 mdt-26 Protein MDT-26 Caenorhabditis elegans Pro-Longevity Decrease mdt-26
172771 mec-8 MEChanosensory abnormality Caenorhabditis elegans Unannotated Increase mec-8
174963 mecr-1 Protein MECR-1 Caenorhabditis elegans Anti-Longevity Increase mecr-1
171872 mek-2 Dual specificity mitogen-activated protein kinase kinase mek-2 Caenorhabditis elegans Pro-Longevity 10% Decrease mek-2
175634 mel-28 Protein MEL-28 Caenorhabditis elegans Anti-Longevity 6% Increase mel-28
178074 mep-1 Mog interacting, Ectopic P granules Caenorhabditis elegans Pro-Longevity 8% Decrease mep-1
181362 mes-1 Maternal Effect Sterile Caenorhabditis elegans Anti-Longevity 60% Increase mes-1
175096 mes-2 Histone-lysine N-methyltransferase mes-2 Caenorhabditis elegans Anti-Longevity 6% Increase mes-2
176183 met-2 Histone-lysine N-methyltransferase met-2 Caenorhabditis elegans Pro-Longevity 23% Decrease met-2
260040 mev-1 Abnormal MEthyl Viologen sensitivity Caenorhabditis elegans Pro-Longevity Decrease mev-1
174752 mfn-1 Protein MFN-1 Caenorhabditis elegans Anti-Longevity 64% Increase mfn-1
179475 mics-1 MItoChondrial Scaffolding protei Caenorhabditis elegans Anti-Longevity 54% Increase mics-1
3565990 mir-124 Caenorhabditis elegans Pro-Longevity 16% Increase mir-124
3565806 mir-238 Caenorhabditis elegans Pro-Longevity 19% Decrease mir-238
3564977 mir-239.1 Caenorhabditis elegans Anti-Longevity 20% Increase mir-239.1
3565660 mir-246 Caenorhabditis elegans Pro-Longevity 10% Decrease mir-246
260162 mir-34 Caenorhabditis elegans Anti-Longevity 62% Increase mir-34
260100 mir-71 Caenorhabditis elegans Pro-Longevity 48% Decrease mir-71
3565575 mir-80 Caenorhabditis elegans Anti-Longevity Increase mir-80
177238 miro-1 Mitochondrial Rho GTPase 1 Caenorhabditis elegans Anti-Longevity 50% Increase miro-1
185682 mkk-4 MKK (MAP Kinase Kinase) homolog Caenorhabditis elegans Anti-Longevity Decrease mkk-4
176050 mml-1 Myc and Mondo-Like Caenorhabditis elegans Pro-Longevity 10% Decrease mml-1
174623 mnk-1 MAP kinase iNtegrating Kinase (MNK) homolog Caenorhabditis elegans Pro-Longevity Decrease mnk-1
171879 mod-5 Modulation Of locomotion Defective Caenorhabditis elegans Pro-Longevity Decrease mod-5
175545 mpk-1 MAP Kinase Caenorhabditis elegans Pro-Longevity 16% Decrease mpk-1
174657 mpz-1 Multiple PDZ domain protein Caenorhabditis elegans Anti-Longevity 31% Increase mpz-1
177736 mpz-2 Temporarily Assigned Gene name Caenorhabditis elegans Anti-Longevity Increase mpz-2
181587 mrp-5 Multidrug Resistance Protein family Caenorhabditis elegans Anti-Longevity Increase mrp-5
186840 mrpl-10 Protein MRPL-10 Caenorhabditis elegans Anti-Longevity 17% Increase mrpl-10
176495 mrpl-12 Protein MRPL-12 Caenorhabditis elegans Anti-Longevity 51% Increase mrpl-12
176903 mrpl-2 Protein MRPL-2 Caenorhabditis elegans Anti-Longevity 54% Increase mrpl-2
172204 mrpl-24 Protein MRPL-24 Caenorhabditis elegans Anti-Longevity 14% Increase mrpl-24
175001 mrpl-37 Protein MRPL-37 Caenorhabditis elegans Anti-Longevity 41% Increase mrpl-37
172164 mrpl-47 Protein MRPL-47 Caenorhabditis elegans Anti-Longevity 20% Increase mrpl-47
174422 mrpl-50 Protein MRPL-50 Caenorhabditis elegans Anti-Longevity 17% Increase mrpl-50
189618 mrps-10 Protein MRPS-10 Caenorhabditis elegans Anti-Longevity 39% Increase mrps-10
172957 mrps-30 Temporarily Assigned Gene name Caenorhabditis elegans Anti-Longevity 21% Increase mrps-30
184770 mrps-33 Protein MRPS-33 Caenorhabditis elegans Anti-Longevity 36% Increase mrps-33
179721 mrps-5 Protein MRPS-5 Caenorhabditis elegans Anti-Longevity 60% Increase mrps-5
184267 mrps-9 Protein MRPS-9 Caenorhabditis elegans Anti-Longevity 60% Increase mrps-9
174207 mtch-1 Protein MTCH-1 Caenorhabditis elegans Anti-Longevity 21% Increase mtch-1
179899 mtl-2 MeTaLlothionein Caenorhabditis elegans Anti-Longevity Increase mtl-2
175490 mtm-3 MTM (myotubularin) famil Caenorhabditis elegans Pro-Longevity Decrease mtm-3
175863 mvk-1 Y42G9A.4b Caenorhabditis elegans Pro-Longevity 14% Decrease mvk-1
175184 mxl-2 MaX-Like Caenorhabditis elegans Pro-Longevity 7% Decrease mxl-2
187898 nac-2 NADC (Na+-coupled dicarboxylate transporter) family Caenorhabditis elegans Anti-Longevity 19% Increase nac-2
176429 nac-3 NADC (Na+-coupled dicarboxylate transporter) family Caenorhabditis elegans Anti-Longevity 15% Increase nac-3
172442 nars-1 asparagiNyl tRNA Synthetase Caenorhabditis elegans Anti-Longevity 11% Increase nars-1
180407 nas-38 Nematode AStacin protease Caenorhabditis elegans Anti-Longevity Increase nas-38
184953 ncbp-2 Nuclear Cap-Binding Protein Caenorhabditis elegans Pro-Longevity 24% Decrease ncbp-2
175582 ndg-4 hypothetical protein Caenorhabditis elegans Anti-Longevity 71% Increase ndg-4
172939 ndk-1 Nucleoside diphosphate kinase Caenorhabditis elegans Anti-Longevity Increase ndk-1
188912 nduf-2.2 NADH Ubiquinone oxidoreductase Fe-S protein Caenorhabditis elegans Anti-Longevity 20% Increase nduf-2.2
174225 nfi-1 NFI (Nuclear Factor I) family Caenorhabditis elegans Pro-Longevity Decrease nfi-1
187340 nhr-119 Protein NHR-119 Caenorhabditis elegans Pro-Longevity 10% Decrease nhr-119
181102 nhr-14 Nuclear Hormone Receptor family Caenorhabditis elegans Anti-Longevity Increase nhr-14
182565 nhr-154 Nuclear Hormone Receptor family Caenorhabditis elegans Anti-Longevity Increase nhr-154
172460 nhr-23 Protein NHR-23 Caenorhabditis elegans Anti-Longevity 5% Increase nhr-23
181432 nhr-25 Protein NHR-25 Caenorhabditis elegans Pro-Longevity 8% Decrease nhr-25
185603 nhr-265 Protein NHR-265 Caenorhabditis elegans Anti-Longevity 4% Increase nhr-265
172839 nhr-49 Nuclear Hormone Receptor family Caenorhabditis elegans Pro-Longevity 56% Decrease nhr-49
191726 nhr-77 Protein NHR-77 Caenorhabditis elegans Pro-Longevity 7% Decrease nhr-77
177551 nhr-8 Nuclear hormone receptor family member nhr-8 Caenorhabditis elegans Pro-Longevity 35% Decrease nhr-8
174242 nhx-2 Na/H eXchanger Caenorhabditis elegans Anti-Longevity 40% Increase nhx-2
3565648 nkcc-1 Protein NKCC-1 Caenorhabditis elegans Anti-Longevity 23% Increase nkcc-1
184647 nlp-7 Neuropeptide-like protein genes family Caenorhabditis elegans Pro-Longevity 10% Decrease nlp-7
180884 nnt-1 Nicotinamide Nucleotide Transhydrogenase Caenorhabditis elegans Pro-Longevity 18% Decrease nnt-1
173437 nol-1 NucleOLar protein Caenorhabditis elegans Anti-Longevity 31% Increase nol-1
171901 nol-5 NucleOLar protein Caenorhabditis elegans Anti-Longevity 15% Increase nol-5
179095 npa-1 Nematode Polyprotein Allergen related Caenorhabditis elegans Anti-Longevity 32% Increase npa-1
172611 npp-2 Nuclear Pore complex Protein Caenorhabditis elegans Pro-Longevity 11% Decrease npp-2
174823 npp-3 Nuclear Pore complex Protein Caenorhabditis elegans Pro-Longevity 14% Decrease npp-3
179503 nrx-1 GLIoTactin (Drosophila neuroligin-like) homolog Caenorhabditis elegans Anti-Longevity Decrease nrx-1
191128 nstp-3 Protein NSTP-3 Caenorhabditis elegans Pro-Longevity 29% Decrease nstp-3
175153 nsun-5 Nop2 (NOP2)/SUN domain family member Caenorhabditis elegans Anti-Longevity 17% Increase nsun-5
176614 ntl-3 NOT-Like (yeast CCR4/NOT complex component) Caenorhabditis elegans Pro-Longevity Decrease ntl-3
181174 nuc-1 abnormal NUClease Caenorhabditis elegans Anti-Longevity Increase nuc-1
176048 numr-1 NUclear localized Metal Responsive Caenorhabditis elegans Pro-Longevity Increase numr-1
176049 numr-2 NUclear localized Metal Responsive Caenorhabditis elegans Pro-Longevity Increase numr-2
174696 nuo-1 NADH Ubiquinone Oxidoreductase Caenorhabditis elegans Anti-Longevity 50% Increase nuo-1
172363 nuo-2 NADH Ubiquinone Oxidoreductase Caenorhabditis elegans Anti-Longevity Increase nuo-2
178404 nuo-3 NADH Ubiquinone Oxidoreductase Caenorhabditis elegans Anti-Longevity 77% Increase nuo-3
176001 nuo-4 NADH Ubiquinone Oxidoreductase Caenorhabditis elegans Anti-Longevity 38% Increase nuo-4
178735 nuo-5 NADH Ubiquinone Oxidoreductase Caenorhabditis elegans Anti-Longevity Increase nuo-5
172438 nuo-6 Protein NUO-6 Caenorhabditis elegans Anti-Longevity 73% Increase nuo-6
188314 ocr-2 Osm-9 and Capsaicin receptor-Related Caenorhabditis elegans Anti-Longevity Increase ocr-2
179098 odr-2 hypothetical protein Caenorhabditis elegans Anti-Longevity 25% Increase odr-2
179806 odr-3 ODoRant response abnormal Caenorhabditis elegans Anti-Longevity 30% Increase odr-3
181403 odr-7 Nuclear hormone receptor family member odr-7 Caenorhabditis elegans Anti-Longevity 27% Increase odr-7
177235 ogdh-1 Protein OGDH-1 Caenorhabditis elegans Anti-Longevity 79% Increase ogdh-1
191737 old-1 Overexpression Longevity Determinant Caenorhabditis elegans Pro-Longevity 65% Increase old-1
181715 osm-1 OSMotic avoidance abnormal Caenorhabditis elegans Anti-Longevity 40% Increase osm-1
177141 osm-3 OSMotic avoidance abnormal Caenorhabditis elegans Anti-Longevity Increase osm-3
180585 osm-5 OSMotic avoidance abnormal Caenorhabditis elegans Anti-Longevity 150% Increase osm-5
179631 osm-6 OSMotic avoidance abnormal Caenorhabditis elegans Anti-Longevity 40% Increase osm-6
172920 pab-1 PolyA Binding protein Caenorhabditis elegans Anti-Longevity 30% Increase pab-1
181473 pab-2 PolyA Binding protein Caenorhabditis elegans Anti-Longevity Increase pab-2
180873 pak-1 Serine/threonine-protein kinase pak-1 Caenorhabditis elegans Unannotated 50% Increase pak-1
178113 par-5 abnormal embryonic PARtitioning of cytoplasm Caenorhabditis elegans Pro-Longevity Increase and Decrease par-5
172950 pash-1 PArtner of DroSHa (DRSH-1 interactor) Caenorhabditis elegans Pro-Longevity 31% Decrease pash-1
172127 pat-10 Paralysed Arrest at Two-fold Caenorhabditis elegans Pro-Longevity 30% Increase pat-10
175504 pat-3 Protein PAT-3 Caenorhabditis elegans Pro-Longevity 28% Decrease pat-3
175175 pat-4 Paralysed Arrest at Two-fold Caenorhabditis elegans Anti-Longevity 24% Increase pat-4
176848 pat-6 Paralysed Arrest at Two-fold Caenorhabditis elegans Anti-Longevity 60% Increase pat-6
173334 pbs-5 Proteasome subunit beta type Caenorhabditis elegans Pro-Longevity 25% Increase pbs-5