Ageing-Associated Genes in Model Organisms

Found 55 results. Showing results 1 to 20.

Entrez ID Symbol Name Organism Longevity influence Max average lifespan change More details
14601 Ghrh growth hormone releasing hormone Mus musculus Anti-Longevity 46% Increase Ghrh
23886 Gdf15 growth differentiation factor 15 Mus musculus Pro-Longevity 43% Increase Gdf15
14600 Ghr Growth hormone receptor Mus musculus Anti-Longevity 40% Increase Ghr
16001 Igf1r Insulin-like growth factor 1 receptor Mus musculus Anti-Longevity 40% Increase Igf1r
18736 Pou1f1 POU domain, class 1, transcription factor 1 Mus musculus Anti-Longevity 40% Increase Pou1f1
13860 Eps8 Epidermal growth factor receptor pathway substrate 8 Mus musculus Anti-Longevity 37% Increase Eps8
56636 Fgf21 fibroblast growth factor 21 Mus musculus Pro-Longevity 36% Increase Fgf21
22166 Txn1 Thioredoxin 1 Mus musculus Pro-Longevity 35% Increase Txn1
16337 Insr Insulin receptor Mus musculus Anti-Longevity 33% Increase Insr
224129 Adcy5 adenylate cyclase 5 Mus musculus Anti-Longevity 30% Increase Adcy5
12850 Coq7 demethyl-Q 7 Mus musculus Anti-Longevity 30% Increase Coq7
18491 Pappa Pregnancy-associated plasma protein A Mus musculus Anti-Longevity 30% Increase Pappa
20416 Shc1 SHC (Src homology 2 domain containing) transforming protein 1 Mus musculus Anti-Longevity 30% Increase Shc1
11607 Agtr1a Angiotensin II receptor, type 1a Mus musculus Anti-Longevity 26% Increase Agtr1a
55961 Slc13a1 Solute carrier family 13 (sodium/sulfate symporters), member 1 Mus musculus Anti-Longevity 25% Increase Slc13a1
13350 Dgat1 diacylglycerol O-acyltransferase 1 Mus musculus Anti-Longevity 23% Increase Dgat1
16150 Ikbkb inhibitor of kappaB kinase beta Mus musculus Anti-Longevity 23% Increase Ikbkb
16491 Kcna3 Potassium voltage-gated channel, shaker-related subfamily, member 3 Mus musculus Anti-Longevity 22% Increase Kcna3
12359 Cat Catalase Mus musculus Pro-Longevity 21% Increase Cat
17869 Myc myelocytomatosis oncogene Mus musculus Anti-Longevity 21% Increase Myc