Ageing-Associated Genes in Model Organisms

Found 909 results. Showing results 1 to 200.

Entrez ID Symbol Name Organism Longevity influence Max average lifespan change More details
852380 AAC3 ADP/ATP Carrier Saccharomyces cerevisiae Anti-Longevity 15% Increase AAC3
855581 AAH1 Adenine AminoHydrolase Saccharomyces cerevisiae Anti-Longevity Increase AAH1
853755 AAT1 Aspartate AminoTransferase Saccharomyces cerevisiae Pro-Longevity 25% Increase AAT1
850714 AAT2 Aspartate AminoTransferase Saccharomyces cerevisiae Pro-Longevity 15% Increase AAT2
850450 ABP1 Actin Binding Protein Saccharomyces cerevisiae Unclear Increase and Decrease ABP1
852925 ACB1 Acyl-CoA-Binding Saccharomyces cerevisiae Anti-Longevity Increase ACB1
852266 ACH1 Ach1p Saccharomyces cerevisiae Necessary For Fitness Decrease ACH1
853230 ACO2 ACOnitase Saccharomyces cerevisiae Unclear Increase and Decrease ACO2
850846 ACS2 Acetyl CoA Synthetase Saccharomyces cerevisiae Pro-Longevity 70% Decrease ACS2
852059 ADA2 transcriptional ADAptor Saccharomyces cerevisiae Necessary For Fitness 50% Decrease ADA2
855222 ADD37 Alpha1-proteinase inhibitor-Degradation Deficient Saccharomyces cerevisiae Necessary For Fitness Decrease ADD37
853629 ADD66 Alpha1-proteinase inhibitor-Degradation Deficient Saccharomyces cerevisiae Necessary For Fitness Decrease ADD66
851272 ADE1 ADEnine requiring Saccharomyces cerevisiae Anti-Longevity Increase ADE1
855501 ADE12 ADEnine requiring Saccharomyces cerevisiae Anti-Longevity Increase ADE12
855149 ADE17 ADEnine requiring Saccharomyces cerevisiae Necessary For Fitness Decrease ADE17
854295 ADE2 ADEnine requiring Saccharomyces cerevisiae Anti-Longevity Increase ADE2
853118 ADE3 ADEnine requiring Saccharomyces cerevisiae Unclear Increase and Decrease ADE3
855346 ADE4 ADEnine requiring Saccharomyces cerevisiae Anti-Longevity Increase ADE4
852617 ADE5,7 ADEnine requiring Saccharomyces cerevisiae Anti-Longevity Increase ADE5,7
852952 ADE6 ADEnine requiring Saccharomyces cerevisiae Anti-Longevity Increase ADE6
854068 ADH1 Alcohol DeHydrogenase Saccharomyces cerevisiae Anti-Longevity 20% Increase ADH1
855349 ADH2 Alcohol DeHydrogenase Saccharomyces cerevisiae Unclear Increase and Decrease ADH2
851812 ADK1 ADenylate Kinase Saccharomyces cerevisiae Necessary For Fitness Decrease ADK1
851802 ADR1 Alcohol Dehydrogenase Regulator Saccharomyces cerevisiae Necessary For Fitness 35% Decrease ADR1
855086 AEP1 ATPase ExPression Saccharomyces cerevisiae Unclear Increase and Decrease AEP1
856737 AFG3 ATPase Family Gene Saccharomyces cerevisiae Anti-Longevity 20% Increase AFG3
856132 AGC1 Aspartate-Glutamate Carrier Saccharomyces cerevisiae Anti-Longevity 30% Increase AGC1
850333 AGP1 high-Affinity Glutamine Permease Saccharomyces cerevisiae Anti-Longevity Increase AGP1
853543 AIM24 Altered Inheritance rate of Mitochondria Saccharomyces cerevisiae Necessary For Fitness Decrease AIM24
855189 AIM36 Altered Inheritance rate of Mitochondria Saccharomyces cerevisiae Necessary For Fitness Decrease AIM36
852351 AKL1 Ark family Kinase-Like protein Saccharomyces cerevisiae Anti-Longevity 20% Increase AKL1
851857 AKR1 AnKyrin Repeat-containing protein Saccharomyces cerevisiae Necessary For Fitness 50% Decrease AKR1
855205 ALD3 ALdehyde Dehydrogenase Saccharomyces cerevisiae Necessary For Fitness Decrease ALD3
854556 ALD4 ALdehyde Dehydrogenase Saccharomyces cerevisiae Anti-Longevity 50% Increase ALD4
856044 ALD6 aldehyde dehydrogenase (NADP(+)) ALD6 Saccharomyces cerevisiae Anti-Longevity Increase ALD6
855764 ALG12 Asparagine-Linked Glycosylation Saccharomyces cerevisiae Anti-Longevity 25% Increase ALG12
852196 ALG3 dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichol alpha-1,3-mannosyltransferase Saccharomyces cerevisiae Anti-Longevity 10% Increase ALG3
855874 ALG5 Asparagine-Linked Glycosylation Saccharomyces cerevisiae Anti-Longevity 50% Increase ALG5
854163 ALG6 dolichyl-P-Glc:Man(9)GlcNAc(2)-PP-dolichol alpha-1,3-glucosyltransferase Saccharomyces cerevisiae Anti-Longevity 15% Increase ALG6
851690 ALT2 ALanine Transaminase Saccharomyces cerevisiae Necessary For Fitness 50% Decrease ALT2
854973 AMD1 AMP Deaminase Saccharomyces cerevisiae Anti-Longevity Increase AMD1
852455 AMN1 Antagonist of Mitotic exit Network Saccharomyces cerevisiae Necessary For Fitness Decrease AMN1
856527 ANS1 Ans1p Saccharomyces cerevisiae Necessary For Fitness 25% Decrease ANS1
3640787 APC10 potential anaphase-promoting complex processivity factor Apc10 Saccharomyces cerevisiae Pro-Longevity Increase and Decrease APC10
854423 APC5 anaphase promoting complex subunit 5 Saccharomyces cerevisiae Unclear Decrease APC5
850792 APC9 anaphase promoting complex subunit 9 Saccharomyces cerevisiae Pro-Longevity Decrease APC9
852589 APE3 AminoPEptidase Saccharomyces cerevisiae Necessary For Fitness Decrease APE3
853723 APL2 clathrin Adaptor Protein complex Large chain Saccharomyces cerevisiae Necessary For Fitness 25% Decrease APL2
855869 APM1 clathrin Adaptor Protein complex Medium chain Saccharomyces cerevisiae Necessary For Fitness 50% Decrease APM1
854986 APT1 Adenine PhosphoribosylTransferase Saccharomyces cerevisiae Anti-Longevity Increase APT1
855660 AQR1 Aqr1p Saccharomyces cerevisiae Unannotated AQR1
856404 ARD1 ARrest Defective Saccharomyces cerevisiae Necessary For Fitness Decrease ARD1
851335 ARF1 ADP-Ribosylation Factor Saccharomyces cerevisiae Necessary For Fitness 50% Decrease ARF1
853374 ARG2 ARGinine requiring Saccharomyces cerevisiae Necessary For Fitness Decrease ARG2
855711 ARK1 Actin Regulating Kinase Saccharomyces cerevisiae Unclear Increase and Decrease ARK1
856173 ARO7 AROmatic amino acid requiring Saccharomyces cerevisiae Necessary For Fitness Decrease ARO7
856530 ARP1 Actin-Related Protein Saccharomyces cerevisiae Necessary For Fitness 40% Decrease ARP1
853327 ASF1 Anti-Silencing Function Saccharomyces cerevisiae Necessary For Fitness 74% Decrease ASF1
854676 ASG1 Activator of Stress Genes Saccharomyces cerevisiae Necessary For Fitness Decrease ASG1
852695 ATG1 AuTophaGy related Saccharomyces cerevisiae Necessary For Fitness 70% Decrease ATG1
850684 ATG10 AuTophaGy related Saccharomyces cerevisiae Necessary For Fitness Decrease ATG10
852518 ATG12 AuTophaGy related Saccharomyces cerevisiae Necessary For Fitness Decrease ATG12
856315 ATG13 AuTophaGy related Saccharomyces cerevisiae Necessary For Fitness Decrease ATG13
852425 ATG14 AuTophaGy related Saccharomyces cerevisiae Necessary For Fitness Decrease ATG14
850432 ATG15 AuTophaGy related Saccharomyces cerevisiae Necessary For Fitness 40% Decrease ATG15
855194 ATG16 AuTophaGy related Saccharomyces cerevisiae Necessary For Fitness Decrease ATG16
851142 ATG17 AuTophaGy related Saccharomyces cerevisiae Necessary For Fitness 70% Decrease ATG17
850577 ATG18 AuTophaGy related Saccharomyces cerevisiae Necessary For Fitness 50% Decrease ATG18
855479 ATG2 AuTophaGy related Saccharomyces cerevisiae Necessary For Fitness Decrease ATG2
856004 ATG21 AuTophaGy related Saccharomyces cerevisiae Necessary For Fitness Decrease ATG21
855937 ATG29 AuTophaGy related Saccharomyces cerevisiae Necessary For Fitness Decrease ATG29
855954 ATG5 AuTophaGy related Saccharomyces cerevisiae Necessary For Fitness Decrease ATG5
856576 ATG7 AuTophaGy related Saccharomyces cerevisiae Necessary For Fitness 70% Decrease ATG7
852200 ATG8 AuTophaGy related Saccharomyces cerevisiae Necessary For Fitness Decrease ATG8
851406 ATG9 AuTophaGy related Saccharomyces cerevisiae Necessary For Fitness Decrease ATG9
856137 ATH1 Acid TreHalase Saccharomyces cerevisiae Necessary For Fitness Decrease ATH1
852177 ATP1 ATP synthase Saccharomyces cerevisiae Unclear Increase and Decrease ATP1
854893 ATP18 ATP synthase Saccharomyces cerevisiae Necessary For Fitness 40% Decrease ATP18
853585 ATP2 ATP synthase F1 subunit gamma Saccharomyces cerevisiae Pro-Longevity 50% Decrease ATP2
852327 ATP3 ATP synthase Saccharomyces cerevisiae Anti-Longevity 50% Increase ATP3
856027 ATP4 ATP synthase Saccharomyces cerevisiae Necessary For Fitness 10% Decrease ATP4
853457 AVT1 Amino acid Vacuolar Transport Saccharomyces cerevisiae Necessary For Fitness Decrease AVT1
852360 BAP2 Branched-chain Amino acid Permease Saccharomyces cerevisiae Necessary For Fitness Decrease BAP2
853974 BAS1 BASal Saccharomyces cerevisiae Anti-Longevity 30% Increase BAS1
853350 BCK1 Bypass of C Kinase Saccharomyces cerevisiae Necessary For Fitness Decrease BCK1
851981 BCS1 ubiquinol-cytochrome c reductase (bc1) Synthesis Saccharomyces cerevisiae Necessary For Fitness Decrease BCS1
854778 BCY1 Bypass of CYclase mutations Saccharomyces cerevisiae Necessary For Fitness Decrease BCY1
852499 BEM1 Bud EMergence Saccharomyces cerevisiae Necessary For Fitness 75% Decrease BEM1
853551 BIR1 Baculoviral IAP Repeat-containing protein Saccharomyces cerevisiae Pro-Longevity Increase BIR1
856924 BMH1 Brain Modulosignalin Homologue Saccharomyces cerevisiae Unclear Increase and Decrease BMH1
851676 BMH2 Brain Modulosignalin Homologue Saccharomyces cerevisiae Pro-Longevity Increase BMH2
853541 BNA2 Biosynthesis of Nicotinic Acid Saccharomyces cerevisiae Anti-Longevity Increase BNA2
850608 BNA6 Biosynthesis of Nicotinic Acid Saccharomyces cerevisiae Pro-Longevity Decrease BNA6
855450 BNI1 Bud Neck Involved Saccharomyces cerevisiae Necessary For Fitness 65% Decrease BNI1
856850 BOI2 Bem1 (One) Interacting protein Saccharomyces cerevisiae Anti-Longevity 25% Increase BOI2
850398 BPH1 Beige Protein Homolog Saccharomyces cerevisiae Necessary For Fitness Decrease BPH1
850645 BPT1 Bile Pigment Transporter Saccharomyces cerevisiae Anti-Longevity 20% Increase BPT1
855787 BRE5 Bre5p Saccharomyces cerevisiae Unclear Increase and Decrease BRE5
851524 BSC1 Bypass of Stop Codon Saccharomyces cerevisiae Anti-Longevity 20% Increase BSC1
851868 BSC2 Bypass of Stop Codon Saccharomyces cerevisiae Anti-Longevity 20% Increase BSC2
850519 BST1 Bst1p Saccharomyces cerevisiae Anti-Longevity 25% Increase BST1
851029 BUD6 BUD site selection Saccharomyces cerevisiae Unannotated BUD6
851459 BUG1 Binder of USO1 and GRH1 Saccharomyces cerevisiae Unclear Increase and Decrease BUG1
854929 BUL2 ubiquitin-ubiquitin ligase BUL2 Saccharomyces cerevisiae Unannotated 16% Increase BUL2
856772 CAJ1 Caj1p Saccharomyces cerevisiae Necessary For Fitness Decrease CAJ1
854292 CAT5 CATabolite repression Saccharomyces cerevisiae Necessary For Fitness 50% Decrease CAT5
856347 CBP2 Cytochrome B mRNA Processing Saccharomyces cerevisiae Necessary For Fitness Decrease CBP2
853085 CBP4 Cytochrome B mRNA Processing Saccharomyces cerevisiae Necessary For Fitness Decrease CBP4
852417 CBP6 Cbp6p Saccharomyces cerevisiae Anti-Longevity 25% Increase CBP6
851491 CBS1 Cbs1p Saccharomyces cerevisiae Anti-Longevity 37% Increase CBS1
855054 CCS1 Ccs1p Saccharomyces cerevisiae Necessary For Fitness 50% Decrease CCS1
851306 CDC13 Cell Division Cycle Saccharomyces cerevisiae Pro-Longevity Decrease CDC13
851019 CDC25 Cdc25p Saccharomyces cerevisiae Anti-Longevity 50% Increase CDC25
850597 CDC26 anaphase promoting complex subunit CDC26 Saccharomyces cerevisiae Pro-Longevity Decrease CDC26
853244 CDC6 Cell Division Cycle Saccharomyces cerevisiae Anti-Longevity 20% Increase CDC6
852881 CDH1 CDC20 Homolog Saccharomyces cerevisiae Necessary For Fitness 45% Decrease CDH1
856911 CHD1 Chromatin organization modifier, Helicase, and DNA-binding domains Saccharomyces cerevisiae Unclear Increase and Decrease CHD1
856099 CHL1 Chl1p Saccharomyces cerevisiae Necessary For Fitness 50% Decrease CHL1
855732 CIT1 CITrate synthase Saccharomyces cerevisiae Necessary For Fitness Decrease CIT1
850361 CIT2 CITrate synthase Saccharomyces cerevisiae Necessary For Fitness Decrease CIT2
854227 CKA2 Casein Kinase Alpha' subunit Saccharomyces cerevisiae Anti-Longevity Increase CKA2
855418 CLA4 CLn Activity dependant Saccharomyces cerevisiae Necessary For Fitness 60% Decrease CLA4
853002 CLB1 CycLin B Saccharomyces cerevisiae Necessary For Fitness 50% Decrease CLB1
856236 CLB2 CycLin B Saccharomyces cerevisiae Necessary For Fitness 50% Decrease CLB2
852657 CLG1 Cyclin-Like Gene Saccharomyces cerevisiae Necessary For Fitness Decrease CLG1
851191 CLN3 Cln3p Saccharomyces cerevisiae Anti-Longevity Decrease CLN3
855287 COA6 Cytochrome Oxidase Assembly Saccharomyces cerevisiae Necessary For Fitness Decrease COA6
852288 COQ1 COenzyme Q Saccharomyces cerevisiae Necessary For Fitness Decrease COQ1
854154 COQ10 COenzyme Q Saccharomyces cerevisiae Necessary For Fitness Decrease COQ10
854057 COQ3 COenzyme Q Saccharomyces cerevisiae Necessary For Fitness Decrease COQ3
854930 COQ5 COenzyme Q Saccharomyces cerevisiae Necessary For Fitness Decrease COQ5
852235 COR1 CORe protein of QH2 cytochrome c reductase Saccharomyces cerevisiae Necessary For Fitness Decrease COR1
855971 COX11 Cytochrome c OXidase Saccharomyces cerevisiae Necessary For Fitness Decrease COX11
856516 COX23 Cytochrome OXidase Saccharomyces cerevisiae Necessary For Fitness 50% Decrease COX23
853267 CPS1 CarboxyPeptidase yscS Saccharomyces cerevisiae Necessary For Fitness Decrease CPS1
854267 CRC1 CaRnitine Carrier Saccharomyces cerevisiae Anti-Longevity 25% Increase CRC1
852324 CSG2 Calcium Sensitive Growth Saccharomyces cerevisiae Necessary For Fitness 40% Decrease CSG2
856142 CSR2 Csr2p Saccharomyces cerevisiae Anti-Longevity Increase CSR2
852330 CST26 Chromosome STability Saccharomyces cerevisiae Anti-Longevity 40% Increase CST26
851843 CTA1 CaTalase A Saccharomyces cerevisiae Anti-Longevity Increase and Decrease CTA1
856254 CTF4 Chromosome Transmission Fidelity Saccharomyces cerevisiae Pro-Longevity Decrease CTF4
851729 CTH1 Cysteine-Three-Histidine Saccharomyces cerevisiae Anti-Longevity 20% Increase CTH1
853718 CTK1 Carboxy-Terminal domain Kinase Saccharomyces cerevisiae Necessary For Fitness 80% Decrease CTK1
856241 CTR1 Copper TRansport Saccharomyces cerevisiae Pro-Longevity Increase and Decrease CTR1
852979 CTT1 Cytosolic catalase T Saccharomyces cerevisiae Unannotated Increase CTT1
855926 CUP9 Cup9p Saccharomyces cerevisiae Necessary For Fitness 30% Decrease CUP9
850376 CWH43 Calcofluor White Hypersensitive Saccharomyces cerevisiae Necessary For Fitness Decrease CWH43
855612 CYB5 Cyb5p Saccharomyces cerevisiae Unannotated CYB5
853507 CYC1 CYtochrome C Saccharomyces cerevisiae Necessary For Fitness 60% Decrease CYC1
854202 CYC2 CYtochrome C Saccharomyces cerevisiae Necessary For Fitness Decrease CYC2
851192 CYC3 CYtochrome C Saccharomyces cerevisiae Necessary For Fitness 20% Decrease CYC3
853452 CYR1 Adenylate cyclase Saccharomyces cerevisiae Anti-Longevity 90% Increase CYR1
853059 CYS4 CYStathionine beta-synthase Saccharomyces cerevisiae Anti-Longevity 50% Increase CYS4
854231 CYT1 ubiquinol--cytochrome-c reductase catalytic subunit CYT1 Saccharomyces cerevisiae Unclear Increase and Decrease CYT1
853775 CYT2 cytochrome c1 heme lyase CYT2 Saccharomyces cerevisiae Necessary For Fitness 25% Decrease CYT2
856423 DAP2 YHR028C Saccharomyces cerevisiae Necessary For Fitness 19% Decrease DAP2
851583 DAS2 Dst1-delta 6-Azauracil Sensitivity Saccharomyces cerevisiae Anti-Longevity 25% Increase DAS2
852984 DBF2 DumbBell Forming Saccharomyces cerevisiae Necessary For Fitness 60% Decrease DBF2
855984 DBP1 Dead Box Protein Saccharomyces cerevisiae Necessary For Fitness 50% Decrease DBP1
852802 DBP3 Dead Box Protein Saccharomyces cerevisiae Anti-Longevity 35% Increase DBP3
850819 DCN1 Defective in Cullin Neddylation Saccharomyces cerevisiae Necessary For Fitness Decrease DCN1
853820 DCW1 Defective Cell Wall Saccharomyces cerevisiae Anti-Longevity Increase DCW1
852500 DER1 Der1p Saccharomyces cerevisiae Anti-Longevity 16% Increase DER1
853738 DGR2 2-Deoxy-Glucose Resistant 2 Saccharomyces cerevisiae Necessary For Fitness Decrease DGR2
853906 DID2 Doa4-Independent Degradation Saccharomyces cerevisiae Necessary For Fitness Decrease DID2
853142 DIE2 Derepression of ITR1 Expression Saccharomyces cerevisiae Anti-Longevity 50% Increase DIE2
851157 DIF1 Damage-regulated Import Facilitator Saccharomyces cerevisiae Necessary For Fitness 20% Decrease DIF1
853381 DLS1 Dls1p Saccharomyces cerevisiae Anti-Longevity 20% Increase DLS1
856569 DNA2 Essential tripartite DNA replication factor with single-stranded DNA-dependent ATPase, ATP-dependent Saccharomyces cerevisiae Pro-Longevity Decrease DNA2
856913 DNF1 Drs2 Neo1 Family Saccharomyces cerevisiae Anti-Longevity 50% Increase DNF1
850686 DNM1 Dnm1p Saccharomyces cerevisiae Anti-Longevity Increase DNM1
851641 DOA4 Degradation Of Alpha Saccharomyces cerevisiae Necessary For Fitness 50% Decrease DOA4
852050 DOT1 histone methyltransferase DOT1 Saccharomyces cerevisiae Necessary For Fitness 24% Decrease DOT1
851699 DPB4 Dpb4p Saccharomyces cerevisiae Necessary For Fitness 15% Decrease DPB4
854703 DPH1 DiPHthamide biosynthesis Saccharomyces cerevisiae Necessary For Fitness Decrease DPH1
855331 DSS1 Deletion of SUV3 Supressor Saccharomyces cerevisiae Unclear Increase and Decrease DSS1
850605 DUG1 Deficient in Utilization of Glutathione Saccharomyces cerevisiae Anti-Longevity Increase DUG1
852584 DUG2 Deficient in Utilization of Glutathione Saccharomyces cerevisiae Necessary For Fitness Decrease DUG2
851457 DUN1 DNA-damage UNinducible Saccharomyces cerevisiae Necessary For Fitness 25% Decrease DUN1
852034 DYN2 DYNein Saccharomyces cerevisiae Necessary For Fitness Decrease DYN2
852370 ECM33 ExtraCellular Mutant Saccharomyces cerevisiae Necessary For Fitness Decrease ECM33
856342 ECM34 ExtraCellular Mutant Saccharomyces cerevisiae Necessary For Fitness Decrease ECM34
854301 EFT1 Elongation Factor Two Saccharomyces cerevisiae Necessary For Fitness 30% Decrease EFT1
851993 EFT2 Elongation Factor Two Saccharomyces cerevisiae Necessary For Fitness Decrease EFT2
856070 EGD1 Enhancer of Gal4 DNA binding Saccharomyces cerevisiae Necessary For Fitness Decrease EGD1
856600 EGD2 Enhancer of Gal4 DNA binding Saccharomyces cerevisiae Necessary For Fitness 20% Decrease EGD2
856019 ELP3 ELongator Protein Saccharomyces cerevisiae Anti-Longevity Increase ELP3
856002 ELP4 ELongator Protein Saccharomyces cerevisiae Anti-Longevity 30% Increase ELP4
852125 EMI1 Early Meiotic Induction Saccharomyces cerevisiae Unclear Increase and Decrease EMI1
852962 ENV11 late ENdosome and Vacuole interface function Saccharomyces cerevisiae Necessary For Fitness 60% Decrease ENV11
855644 EOS1 Eos1p Saccharomyces cerevisiae Anti-Longevity 24% Increase EOS1
855441 ERG24 ERGosterol biosynthesis Saccharomyces cerevisiae Necessary For Fitness 50% Decrease ERG24
855029 ERG5 ERGosterol biosynthesis Saccharomyces cerevisiae Necessary For Fitness 35% Decrease ERG5
855003 ERG6 ERGosterol biosynthesis Saccharomyces cerevisiae Necessary For Fitness 50% Decrease ERG6
854909 ERO1 ER oxidoreductin Saccharomyces cerevisiae Anti-Longevity 28% Increase ERO1
856152 ERV2 Essential for Respiration and Viability Saccharomyces cerevisiae Anti-Longevity Increase ERV2
851965 ESC2 Establishment of Silent Chromatin Saccharomyces cerevisiae Necessary For Fitness 50% Decrease ESC2
853971 ESL2 Est1A/B-Smg6/5-Like Saccharomyces cerevisiae Necessary For Fitness Decrease ESL2
852314 ETR1 2-Enoyl Thioester Reductase Saccharomyces cerevisiae Necessary For Fitness 45% Decrease ETR1
852130 EUG1 ER protein Unnecessary for Growth Saccharomyces cerevisiae Unclear Increase and Decrease EUG1