Human Ageing-Associated Genes

Found 305 results. Showing results 1 to 305.

HAGRID HGNC symbol Common name Display entry
78ABL1ABL proto-oncogene 1, non-receptor tyrosine kinaseABL1
255ADCY5adenylate cyclase 5ADCY5
187AGPAT21-acylglycerol-3-phosphate O-acyltransferase 2AGPAT2
264AGTR1angiotensin II receptor, type 1AGTR1
135AIFM1apoptosis-inducing factor, mitochondrion-associated, 1AIFM1
35AKT1v-akt murine thymoma viral oncogene homolog 1AKT1
195APEX1APEX nuclease (multifunctional DNA repair enzyme) 1APEX1
102APOC3apolipoprotein C-IIIAPOC3
138APOEapolipoprotein EAPOE
137APPamyloid beta (A4) precursor proteinAPP
110ARandrogen receptorAR
249ARHGAP1Rho GTPase activating protein 1ARHGAP1
251ARNTLaryl hydrocarbon receptor nuclear translocator-likeARNTL
193ATF2activating transcription factor 2ATF2
9ATMATM serine/threonine kinaseATM
146ATP5OATP synthase, H+ transporting, mitochondrial F1 complex, O subunitATP5O
231ATRATR serine/threonine kinaseATR
278BAK1BCL2-antagonist/killer 1BAK1
119BAXBCL2-associated X proteinBAX
69BCL2B-cell CLL/lymphoma 2BCL2
191BDNFbrain-derived neurotrophic factorBDNF
68BLMBloom syndrome, RecQ helicase-likeBLM
188BMI1BMI1 proto-oncogene, polycomb ring fingerBMI1
61BRCA1breast cancer 1, early onsetBRCA1
79BRCA2breast cancer 2, early onsetBRCA2
186BSCL2Berardinelli-Seip congenital lipodystrophy 2 (seipin)BSCL2
197BUB1BBUB1 mitotic checkpoint serine/threonine kinase BBUB1B
240BUB3BUB3 mitotic checkpoint proteinBUB3
287C1QAcomplement component 1, q subcomponent, A chainC1QA
133CACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunitCACNA1A
177CCNA2cyclin A2CCNA2
250CDC42cell division cycle 42CDC42
201CDK1cyclin-dependent kinase 1CDK1
299CDK7cyclin-dependent kinase 7CDK7
284CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)CDKN1A
226CDKN2Acyclin-dependent kinase inhibitor 2ACDKN2A
288CDKN2Bcyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)CDKN2B
88CEBPACCAAT/enhancer binding protein (C/EBP), alphaCEBPA
89CEBPBCCAAT/enhancer binding protein (C/EBP), betaCEBPB
262CETPcholesteryl ester transfer protein, plasmaCETP
247CHEK2checkpoint kinase 2CHEK2
265CISD2CDGSH iron sulfur domain 2CISD2
252CLOCKclock circadian regulatorCLOCK
282CNR1cannabinoid receptor 1 (brain)CNR1
132COQ7coenzyme Q7 homolog, ubiquinone (yeast)COQ7
192CREB1cAMP responsive element binding protein 1CREB1
64CREBBPCREB binding proteinCREBBP
244CSNK1Ecasein kinase 1, epsilonCSNK1E
304CTF1cardiotrophin 1CTF1
206CTGFconnective tissue growth factorCTGF
223CTNNB1catenin (cadherin-associated protein), beta 1, 88kDaCTNNB1
228DBN1drebrin 1DBN1
203DDIT3DNA-damage-inducible transcript 3DDIT3
291DGAT1diacylglycerol O-acyltransferase 1DGAT1
225DLL3delta-like 3 (Drosophila)DLL3
18E2F1E2F transcription factor 1E2F1
189EEF1A1eukaryotic translation elongation factor 1 alpha 1EEF1A1
266EEF1E1eukaryotic translation elongation factor 1 epsilon 1EEF1E1
103EEF2eukaryotic translation elongation factor 2EEF2
260EFEMP1EGF containing fibulin-like extracellular matrix protein 1EFEMP1
48EGFepidermal growth factorEGF
40EGFRepidermal growth factor receptorEGFR
76EGR1early growth response 1EGR1
289EIF5A2eukaryotic translation initiation factor 5A2EIF5A2
94EP300E1A binding protein p300EP300
52EPORerythropoietin receptorEPOR
267EPS8epidermal growth factor receptor pathway substrate 8EPS8
41ERBB2erb-b2 receptor tyrosine kinase 2ERBB2
149ERCC1excision repair cross-complementation group 1ERCC1
11ERCC2excision repair cross-complementation group 2ERCC2
104ERCC3excision repair cross-complementation group 3ERCC3
261ERCC4excision repair cross-complementation group 4ERCC4
109ERCC5excision repair cross-complementation group 5ERCC5
92ERCC6excision repair cross-complementation group 6ERCC6
12ERCC8excision repair cross-complementation group 8ERCC8
216ESR1estrogen receptor 1ESR1
115FASFas cell surface death receptorFAS
114FEN1flap structure-specific endonuclease 1FEN1
293FGF21fibroblast growth factor 21FGF21
259FGF23fibroblast growth factor 23FGF23
169FGFR1fibroblast growth factor receptor 1FGFR1
171FLT1fms-related tyrosine kinase 1FLT1
50FOSFBJ murine osteosarcoma viral oncogene homologFOS
131FOXM1forkhead box M1FOXM1
124FOXO1forkhead box O1FOXO1
123FOXO3forkhead box O3FOXO3
183FOXO4forkhead box O4FOXO4
237GCLCglutamate-cysteine ligase, catalytic subunitGCLC
238GCLMglutamate-cysteine ligase, modifier subunitGCLM
26GH1growth hormone 1GH1
1GHRgrowth hormone receptorGHR
2GHRHgrowth hormone releasing hormoneGHRH
222GHRHRgrowth hormone releasing hormone receptorGHRHR
153GPX1glutathione peroxidase 1GPX1
257GPX4glutathione peroxidase 4GPX4
122GRB2growth factor receptor-bound protein 2GRB2
295GSK3Aglycogen synthase kinase 3 alphaGSK3A
97GSK3Bglycogen synthase kinase 3 betaGSK3B
154GSRglutathione reductaseGSR
155GSSglutathione synthetaseGSS
156GSTA4glutathione S-transferase alpha 4GSTA4
157GSTP1glutathione S-transferase pi 1GSTP1
111GTF2H2general transcription factor IIH, polypeptide 2, 44kDaGTF2H2
212H2AFXH2A histone family, member XH2AFX
196HBP1HMG-box transcription factor 1HBP1
151HDAC1histone deacetylase 1HDAC1
207HDAC2histone deacetylase 2HDAC2
25HDAC3histone deacetylase 3HDAC3
101HELLShelicase, lymphoid-specificHELLS
184HESX1HESX homeobox 1HESX1
253HIC1hypermethylated in cancer 1HIC1
65HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)HIF1A
176HMGB1high mobility group box 1HMGB1
178HMGB2high mobility group box 2HMGB2
213HOXB7homeobox B7HOXB7
214HOXC4homeobox C4HOXC4
38HRASHarvey rat sarcoma viral oncogene homologHRAS
125HSF1heat shock transcription factor 1HSF1
74HSP90AA1heat shock protein 90kDa alpha (cytosolic), class A member 1HSP90AA1
160HSPA1Aheat shock 70kDa protein 1AHSPA1A
161HSPA1Bheat shock 70kDa protein 1BHSPA1B
199HSPA8heat shock 70kDa protein 8HSPA8
152HSPA9heat shock 70kDa protein 9 (mortalin)HSPA9
159HSPD1heat shock 60kDa protein 1 (chaperonin)HSPD1
294HTRA2HtrA serine peptidase 2HTRA2
28IGF1insulin-like growth factor 1 (somatomedin C)IGF1
15IGF1Rinsulin-like growth factor 1 receptorIGF1R
29IGF2insulin-like growth factor 2IGF2
279IGFBP2insulin-like growth factor binding protein 2, 36kDaIGFBP2
73IGFBP3insulin-like growth factor binding protein 3IGFBP3
297IKBKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase betaIKBKB
46IL2interleukin 2IL2
49IL2RGinterleukin 2 receptor, gammaIL2RG
144IL6interleukin 6IL6
167IL7interleukin 7IL7
27IL7Rinterleukin 7 receptorIL7R
42INSRinsulin receptorINSR
32IRS1insulin receptor substrate 1IRS1
34IRS2insulin receptor substrate 2IRS2
215JAK2Janus kinase 2JAK2
172JUNjun proto-oncogeneJUN
45JUNDjun D proto-oncogeneJUND
268KCNA3potassium channel, voltage gated shaker related subfamily A, member 3KCNA3
218LEPRleptin receptorLEPR
181LMNB1lamin B1LMNB1
134LRP2low density lipoprotein receptor-related protein 2LRP2
179MAP3K5mitogen-activated protein kinase kinase kinase 5MAP3K5
168MAPK14mitogen-activated protein kinase 14MAPK14
175MAPK3mitogen-activated protein kinase 3MAPK3
163MAPK8mitogen-activated protein kinase 8MAPK8
174MAPK9mitogen-activated protein kinase 9MAPK9
205MAPTmicrotubule-associated protein tauMAPT
208MAXMYC associated factor XMAX
210MDM2MDM2 proto-oncogene, E3 ubiquitin protein ligaseMDM2
173MED1mediator complex subunit 1MED1
290MIFmacrophage migration inhibitory factor (glycosylation-inhibiting factor)MIF
243MLH1mutL homolog 1MLH1
127MSRAmethionine sulfoxide reductase AMSRA
158MT-CO1mitochondrially encoded cytochrome c oxidase IMT-CO1
292MT1Emetallothionein 1EMT1E
221MTORmechanistic target of rapamycin (serine/threonine kinase)MTOR
209MXD1MAX dimerization protein 1MXD1
90MXI1MAX interactor 1, dimerization proteinMXI1
39MYCv-myc avian myelocytomatosis viral oncogene homologMYC
43NCOR1nuclear receptor corepressor 1NCOR1
276NCOR2nuclear receptor corepressor 2NCOR2
307NFE2L1nuclear factor, erythroid 2-like 1NFE2L1
283NFE2L2nuclear factor, erythroid 2-like 2NFE2L2
82NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1NFKB1
20NFKB2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)NFKB2
219NFKBIAnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alphaNFKBIA
31NGFnerve growth factor (beta polypeptide)NGF
37NGFRnerve growth factor receptorNGFR
75NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)NR3C1
24NRG1neuregulin 1NRG1
296NUDT1nudix (nucleoside diphosphate linked moiety X)-type motif 1NUDT1
254PAPPApregnancy-associated plasma protein A, pappalysin 1PAPPA
60PARP1poly (ADP-ribose) polymerase 1PARP1
248PCK1phosphoenolpyruvate carboxykinase 1 (soluble)PCK1
162PCMT1protein-L-isoaspartate (D-aspartate) O-methyltransferasePCMT1
113PCNAproliferating cell nuclear antigenPCNA
47PDGFBplatelet-derived growth factor beta polypeptidePDGFB
285PDGFRAplatelet-derived growth factor receptor, alpha polypeptidePDGFRA
51PDGFRBplatelet-derived growth factor receptor, beta polypeptidePDGFRB
87PDPK13-phosphoinositide dependent protein kinase 1PDPK1
58PEX5peroxisomal biogenesis factor 5PEX5
286PIK3CAphosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alphaPIK3CA
36PIK3CBphosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit betaPIK3CB
185PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)PIK3R1
62PIN1peptidylprolyl cis/trans isomerase, NIMA-interacting 1PIN1
10PLAUplasminogen activator, urokinasePLAU
57PLCG2phospholipase C, gamma 2 (phosphatidylinositol-specific)PLCG2
242PMCHpro-melanin-concentrating hormonePMCH
96PMLpromyelocytic leukemiaPML
204POLA1polymerase (DNA directed), alpha 1, catalytic subunitPOLA1
236POLBpolymerase (DNA directed), betaPOLB
118POLD1polymerase (DNA directed), delta 1, catalytic subunitPOLD1
72POLGpolymerase (DNA directed), gammaPOLG
142PON1paraoxonase 1PON1
4POU1F1POU class 1 homeobox 1POU1F1
55PPARAperoxisome proliferator-activated receptor alphaPPARA
263PPARGperoxisome proliferator-activated receptor gammaPPARG
256PPARGC1Aperoxisome proliferator-activated receptor gamma, coactivator 1 alphaPPARGC1A
246PPM1Dprotein phosphatase, Mg2+/Mn2+ dependent, 1DPPM1D
227PPP1CAprotein phosphatase 1, catalytic subunit, alpha isozymePPP1CA
141PRDX1peroxiredoxin 1PRDX1
99PRKCAprotein kinase C, alphaPRKCA
54PRKCDprotein kinase C, deltaPRKCD
106PRKDCprotein kinase, DNA-activated, catalytic polypeptidePRKDC
5PROP1PROP paired-like homeobox 1PROP1
224PSEN1presenilin 1PSEN1
63PTENphosphatase and tensin homologPTEN
198PTGS2prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)PTGS2
166PTK2protein tyrosine kinase 2PTK2
165PTK2Bprotein tyrosine kinase 2 betaPTK2B
33PTPN1protein tyrosine phosphatase, non-receptor type 1PTPN1
19PTPN11protein tyrosine phosphatase, non-receptor type 11PTPN11
280PYCR1pyrroline-5-carboxylate reductase 1PYCR1
84RAD51RAD51 recombinaseRAD51
147RAD52RAD52 homolog, DNA repair proteinRAD52
241RAE1ribonucleic acid export 1RAE1
120RB1retinoblastoma 1RB1
128RECQL4RecQ helicase-like 4RECQL4
143RELAv-rel avian reticuloendotheliosis viral oncogene homolog ARELA
56RETret proto-oncogeneRET
303RICTORRPTOR independent companion of MTOR, complex 2RICTOR
67RPA1replication protein A1, 70kDaRPA1
70S100BS100 calcium binding protein BS100B
182SDHCsuccinate dehydrogenase complex, subunit C, integral membrane protein, 15kDaSDHC
301SERPINE1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1SERPINE1
3SHC1SHC (Src homology 2 domain containing) transforming protein 1SHC1
200SIN3ASIN3 transcription regulator family member ASIN3A
150SIRT1sirtuin 1SIRT1
275SIRT3sirtuin 3SIRT3
239SIRT6sirtuin 6SIRT6
269SIRT7sirtuin 7SIRT7
270SLC13A1solute carrier family 13 (sodium/sulfate symporter), member 1SLC13A1
140SNCGsynuclein, gamma (breast cancer-specific protein 1)SNCG
271SOCS2suppressor of cytokine signaling 2SOCS2
130SOD1superoxide dismutase 1, solubleSOD1
129SOD2superoxide dismutase 2, mitochondrialSOD2
170SP1Sp1 transcription factorSP1
302SPRTNSprT-like N-terminal domainSPRTN
298SQSTM1sequestosome 1SQSTM1
100SSTR3somatostatin receptor 3SSTR3
22STAT3signal transducer and activator of transcription 3 (acute-phase response factor)STAT3
23STAT5Asignal transducer and activator of transcription 5ASTAT5A
21STAT5Bsignal transducer and activator of transcription 5BSTAT5B
93STK11serine/threonine kinase 11STK11
245STUB1STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligaseSTUB1
211SUMO1small ubiquitin-like modifier 1SUMO1
277SUN1Sad1 and UNC84 domain containing 1SUN1
180TAF1TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDaTAF1
194TBPTATA box binding proteinTBP
59TCF3transcription factor 3TCF3
7TERCtelomerase RNA componentTERC
105TERF1telomeric repeat binding factor (NIMA-interacting) 1TERF1
116TERF2telomeric repeat binding factor 2TERF2
8TERTtelomerase reverse transcriptaseTERT
190TFAP2Atranscription factor AP-2 alpha (activating enhancer binding protein 2 alpha)TFAP2A
202TFDP1transcription factor Dp-1TFDP1
91TGFB1transforming growth factor, beta 1TGFB1
86TNFtumor necrosis factorTNF
83TOP1topoisomerase (DNA) ITOP1
80TOP2Atopoisomerase (DNA) II alphaTOP2A
81TOP2Btopoisomerase (DNA) II betaTOP2B
148TOP3Btopoisomerase (DNA) III betaTOP3B
6TP53tumor protein p53TP53
274TP53BP1tumor protein p53 binding protein 1TP53BP1
234TP63tumor protein p63TP63
281TP73tumor protein p73TP73
273TPP2tripeptidyl peptidase IITPP2
305TRAP1TNF receptor-associated protein 1TRAP1
306TRPV1transient receptor potential cation channel, subfamily V, member 1TRPV1
66UBBubiquitin BUBB
85UBE2Iubiquitin-conjugating enzyme E2IUBE2I
136UCHL1ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)UCHL1
258UCP1uncoupling protein 1 (mitochondrial, proton carrier)UCP1
235UCP2uncoupling protein 2 (mitochondrial, proton carrier)UCP2
232UCP3uncoupling protein 3 (mitochondrial, proton carrier)UCP3
71VCPvalosin containing proteinVCP
77VEGFAvascular endothelial growth factor AVEGFA
13WRNWerner syndrome, RecQ helicase-likeWRN
126XPAxeroderma pigmentosum, complementation group AXPA
112XRCC5X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)XRCC5
117XRCC6X-ray repair complementing defective repair in Chinese hamster cells 6XRCC6
164YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zetaYWHAZ
233ZMPSTE24zinc metallopeptidase STE24ZMPSTE24