GenAge entry for HBP1 (Homo sapiens)

Gene name (HAGRID: 196)

HGNC symbol
HBP1 
Aliases
 
Common name
HMG-box transcription factor 1 

Potential relevance to the human ageing process

Main reason for selection
Entry selected based on evidence showing that the gene product to be a target of genes previously linked to ageing
Description

HBP1 has been related to DNA unwinding and stress response [860]. In mice, HBP1 and other HMG chromosomal proteins have been shown to suffer alterations at various levels during ageing [791], but HBP1 has not been directly related to human ageing.

Cytogenetic information

Cytogenetic band
7q22-q31
Location
107,169,015 bp to 107,202,529 bp
Orientation
Plus strand
Display region using the UCSC Genome Browser (GRCh38/hg38)

Protein information

Gene Ontology
Process: GO:0006351; transcription, DNA-templated
GO:0006355; regulation of transcription, DNA-dependent
GO:0007050; cell cycle arrest
GO:0016055; Wnt receptor signaling pathway
GO:0043268; positive regulation of potassium ion transport
Cellular component: GO:0005634; nucleus
Function: GO:0003677; DNA binding
GO:0003723; RNA binding
GO:0005515; protein binding
Show all GO terms

Protein interactions and network

Protein-protein interacting partners in GenAge
TP53, AR, RB1, MAPK14
STRING interaction network
Protein-Protein network diagram for HBP1

Retrieve sequences for HBP1

Promoter
Promoter
ORF
ORF
CDS
CDS

Homologs in model organisms

Danio rerio
hbp1
Mus musculus
Hbp1
Rattus norvegicus
Hbp1

Selected references

External links

EPD
HS_HBP1
ORF Accession
NM_012257
CDS Accession
NP_036389
OMIM
HPRD
01602
Ensembl
HBP1
UniProt/Swiss-Prot
HBP1_HUMAN
GeneCards
HBP1
Entrez Gene
26959
UniGene
162032
GenAtlas
HBP1
Internet
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