GenAge entry for GSTA4 (Homo sapiens)

Gene name (HAGRID: 156)

HGNC symbol
GSTA4 
Aliases
 
Common name
glutathione S-transferase alpha 4 

Potential relevance to the human ageing process

Main reason for selection
Entry selected based on evidence linking the gene product to a pathway or mechanism linked to ageing
Description

GSTA4 is part of the glutathione system involved in oxidative protection [44]. Expression of GSTA4 increases in the aged rat cerebral cortex [746]. There is no causal evidence, however, linking GSTA4 to ageing in humans or in model organisms.

Cytogenetic information

Cytogenetic band
6p12.1
Location
52,977,948 bp to 52,995,380 bp
Orientation
Minus strand
Display region using the UCSC Genome Browser (GRCh38/hg38)

Protein information

Gene Ontology
Process: GO:0006749; glutathione metabolic process
GO:0006805; xenobiotic metabolic process
GO:0044281; small molecule metabolic process
GO:1901687; glutathione derivative biosynthetic process
Cellular component: GO:0005829; cytosol
Function: GO:0004364; glutathione transferase activity
GO:0042803; protein homodimerization activity
Show all GO terms

Protein interactions and network

No interactions in records.

Retrieve sequences for GSTA4

ORF
ORF
CDS
CDS

Homologs in model organisms

No homologs found

In other databases

LongevityMap
  • This gene is present as GSTA4

Selected references

External links

EPD
ORF Accession
NM_001512
CDS Accession
NP_001503
OMIM
605450
HPRD
06899
Ensembl
GSTA4
UniProt/Swiss-Prot
GSTA4_HUMAN
GeneCards
GSTA4
Entrez Gene
2941
UniGene
485557
GenAtlas
GSTA4
Internet
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