- Symbol
- tmem-135
- Name
- K02G10.3
- Organism
- Caenorhabditis elegans (AnAge)
- Observations
- Deletion of the tmem135 orthologue in C. elegans caused a 41.8% (62.8%) reduction in fat stores, a reduction in mitochondrial action potential and decreased longevity of the worm. In stark contrast, C. elegans transgenic animals overexpressing TMEM-135 exhibited increased longevity upon exposure to cold stress.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- Deletion
- Primary reference
-
- Danio rerio
- tmem135
- Drosophila melanogaster
- CG11737
- Drosophila melanogaster
- CG31259
- Drosophila melanogaster
- CG31454
- Homo sapiens
- TMEM135
- Mus musculus
- Tmem135
- Rattus norvegicus
- Tmem135
- WormBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (180740)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for tmem-135 (Caenorhabditis elegans)