Caenorhabditis elegansGenAge entry for tlf-1 (Caenorhabditis elegans)

Gene information (ID: 675)

Symbol
tlf-1
Name
TBP-Like Factor
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Transcription factor

Potential relevance to longevity and/or ageing

Observations
RNA interference decreased median lifespan by 33% in wild type animals and 49% in daf-2 mutants.
% change in avg or median lifespan
Median lifespan is 33% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    CellAge
    • A homolog of this gene for Homo sapiens is present as TBPL1

    Homologs in other organisms

    Danio rerio
    tbpl1
    Drosophila melanogaster
    Trf2
    Homo sapiens
    TBPL1
    Mus musculus
    Tbpl1
    Rattus norvegicus
    Tbpl1
    Saccharomyces cerevisiae
    SPT15

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (172676)
    Homologues
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    UniProt
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    Internet
    Search Google or Search Google Scholar