Caenorhabditis elegansGenAge entry for sem-5 (Caenorhabditis elegans)

Gene information (ID: 596)

Symbol
sem-5
Name
SEx Muscle abnormal
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Regulates RAS-MAP and -IP3 signal transduction

Potential relevance to longevity and/or ageing

Observations
RNA interference in adulthood increased mean lifespan by 24%.
% change in avg or median lifespan
Average lifespan is 24% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as GRB2
    LongevityMap
    • A homolog of this gene for Homo sapiens is present as GRB2

    Homologs in other organisms

    Danio rerio
    grapa
    Danio rerio
    grb2b
    Danio rerio
    grb2a
    Danio rerio
    grapb
    Drosophila melanogaster
    drk
    Homo sapiens
    GRB2
    Homo sapiens
    GRAP
    Homo sapiens
    GRAPL
    Mus musculus
    Grap
    Mus musculus
    Grb2
    Rattus norvegicus
    Grap
    Rattus norvegicus
    Grb2
    Rattus norvegicus
    Grb2

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (181055)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
    Search Google or Search Google Scholar