GenAge entry for gst-10 (Caenorhabditis elegans)
Gene information (ID: 328)
- Symbol
- gst-10
- Name
- Glutathione S-Transferase
- Organism
- Caenorhabditis elegans (AnAge)
- Known functions and activities
- Conjugation of the lipid peroxidation product 4-hydroxynonenal (4-HNE)
Potential relevance to longevity and/or ageing
- Observations
- Overexpression resulted in transgenic animals with enhanced stress resistance and increased lifespan by 13-22%.
- % change in avg or median lifespan
- Lifespan is 13-22% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Overexpression
- Longevity Category
- Pro-Longevity
- Primary reference
-
- Observations
- RNAi resulted in a decreased maximum lifespan.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- RNA interference
- Longevity Category
- Pro-Longevity
- Primary reference
-
Homologs in other organisms
No homologs found
External links
- WormBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (178725)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar