Caenorhabditis elegansGenAge entry for tald-1 (Caenorhabditis elegans)

Gene information (ID: 2213)

Symbol
tald-1
Name
Transaldolase
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
Downregulation of tald-1 in worms increased lifespan by 14%. This increase only occurred if knock-down took place throughout development. Tald-1 downregulation in adult worms had no effect on lifespan.
% change in avg or median lifespan
Mean lifespan is 14% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Saccharomyces cerevisiae is present as TAL1
    • This gene is present as Y24D9A.8

    Homologs in other organisms

    Danio rerio
    taldo1
    Drosophila melanogaster
    Tal
    Homo sapiens
    TALDO1
    Mus musculus
    Taldo1
    Rattus norvegicus
    Taldo1
    Saccharomyces cerevisiae
    NQM1
    Saccharomyces cerevisiae
    TAL1
    Schizosaccharomyces pombe
    tal1

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (177202)
    Homologues
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    UniProt
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    Internet
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