Caenorhabditis elegansGenAge entry for lipl-4 (Caenorhabditis elegans)

Gene information (ID: 1881)

Symbol
lipl-4
Name
LIPase Like
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
Constitutive transgenic expression of lipl-4 in the intestine results in a 55% mean lifespan increase compared to wild-type.
% change in max lifespan
Maximum lifespan is aproximately 25% higher.
% change in avg or median lifespan
Mean lifespan is 55% higher.
Lifespan Effect
Increase
Genetic Manipulation
Overexpression
Longevity Category
Pro-Longevity
Primary reference
    Observations
    Constitutive expression of lipl-4 (K04A8.5) in the intestine extends worm mean lifespan by 24%.
    % change in avg or median lifespan
    Mean lifespan is 24% higher.
    Lifespan Effect
    Increase
    Genetic Manipulation
    Overexpression
    Longevity Category
    Pro-Longevity
    Primary reference

      Homologs in other organisms

      Danio rerio
      lipf
      Homo sapiens
      LIPF
      Homo sapiens
      LIPJ
      Homo sapiens
      LIPK
      Mus musculus
      Lipo1
      Mus musculus
      Lipo1
      Mus musculus
      Lipo3
      Mus musculus
      Lipo5
      Mus musculus
      Lipk
      Mus musculus
      Lipo4
      Mus musculus
      Lipo2
      Mus musculus
      Lipf
      Rattus norvegicus
      LOC100360690
      Rattus norvegicus
      Lipk
      Rattus norvegicus
      Lipo1
      Rattus norvegicus
      Lipf
      Saccharomyces cerevisiae
      TGL1

      External links

      WormBase
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      Entrez Gene
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      Homologues
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      UniProt
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      Internet
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