GenAge entry for FOB1 (Saccharomyces cerevisiae)
Gene information (ID: 284)
- Symbol
- FOB1
- Aliases
- HRM1
- Name
- Fob1p
- Organism
- Saccharomyces cerevisiae (AnAge)
Potential relevance to longevity and/or ageing
- Observations
- Knocking out this gene extends lifespan by 30-50%.
- % change in avg or median lifespan
- Lifespan is 30-50% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Knockout
- Longevity Category
- Anti-Longevity
- Primary reference
-
- Observations
- Deletion of fob1 causes extension in the short life span of the sir2 mutant extended by ~50%
- % change in avg or median lifespan
- Replicative lifespan is approximately 50% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Deletion
- Longevity Category
- Anti-Longevity
- Primary reference
-
- Observations
- About 20% mean replicative lifespan increase
- % change in avg or median lifespan
- Replicative lifespan is 20% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Deletion
- Longevity Category
- Anti-Longevity
- Primary reference
-
- Observations
- Replicative lifespan increased by 25% in the alpha strain and by 10% in a strain
- % change in avg or median lifespan
- Replicative lifespan is 10-25% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Deletion
- Longevity Category
- Anti-Longevity
- Primary reference
-
- Observations
- Mean chronological lifespan strongly increased in the a strain
- Lifespan Effect
- Increase
- Genetic Manipulation
- Deletion
- Longevity Category
- Anti-Longevity
- Primary reference
-
Homologs in other organisms
No homologs found
External links
- Saccharomyces Genome Database
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (851688)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar