Saccharomyces cerevisiaeGenAge entry for HST1 (Saccharomyces cerevisiae)

Gene information (ID: 1074)

Symbol
HST1
Name
Homolog of SIR Two (SIR2)
Organism
Saccharomyces cerevisiae (AnAge)

Potential relevance to longevity and/or ageing

Observations
Mean replicative lifespan decreased in the alpha and a strain
Lifespan Effect
Decrease
Genetic Manipulation
Deletion
Longevity Category
Necessary for fitness
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Caenorhabditis elegans is present as sir-2.1
    • A homolog of this gene for Drosophila melanogaster is present as Sir2
    • A homolog of this gene for Mus musculus is present as Sirt1
    • A homolog of this gene for Drosophila melanogaster is present as Sirt4
    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as SIRT1
    GenDR gene manipulations
    • A homolog of this gene for Drosophila melanogaster is present as Sir2
    • A homolog of this gene for Mus musculus is present as Sirt1
    • A homolog of this gene for Caenorhabditis elegans is present as sir-2.1
    • This gene is present as HST1
    LongevityMap
    • A homolog of this gene for Homo sapiens is present as SIRT1
    CellAge
    • A homolog of this gene for Homo sapiens is present as SIRT1

    Homologs in other organisms

    Caenorhabditis elegans
    sir-2.3
    Caenorhabditis elegans
    sir-2.1
    Caenorhabditis elegans
    sir-2.2
    Danio rerio
    sirt4
    Danio rerio
    sirt5
    Danio rerio
    sirt1
    Drosophila melanogaster
    Sir2
    Drosophila melanogaster
    Sirt4
    Homo sapiens
    SIRT5
    Homo sapiens
    SIRT1
    Homo sapiens
    SIRT4
    Mus musculus
    Sirt1
    Mus musculus
    Sirt5
    Mus musculus
    Sirt4
    Rattus norvegicus
    Sirt1
    Rattus norvegicus
    Sirt4
    Rattus norvegicus
    Sirt5
    Schizosaccharomyces pombe
    sir2

    External links

    Saccharomyces Genome Database
    Search
    Ensembl
    Search
    Entrez Gene
    View on Entrez Gene database (854086)
    Homologues
    Search HomoloGene
    UniProt
    Search
    Internet
    Search Google or Search Google Scholar