Saccharomyces cerevisiaeGenAge entry for AEP1 (Saccharomyces cerevisiae)

Gene information (ID: 1020)

Symbol
AEP1
Aliases
NCA1
Name
ATPase ExPression
Organism
Saccharomyces cerevisiae (AnAge)

Potential relevance to longevity and/or ageing

Observations
The life span of cbs1D, cbp6D, suv3D, dss1D, pet122D, pet309D, and aep1D mutants was examined to check if the absence of members of the MTC module other than Sov1p leads to life span extension. Indeed, all those mutants were long-lived.
% change in avg or median lifespan
Average lifespan is 30% higher.
Lifespan Effect
Increase
Genetic Manipulation
Mutation
Longevity Category
Anti-Longevity
Primary reference
    Observations
    Mean chronological lifespan decreased in the a strain
    Lifespan Effect
    Decrease
    Genetic Manipulation
    Deletion
    Longevity Category
    Necessary for fitness
    Primary reference
      Observations
      Mean replicative lifespan decreased in the alpha and a strain
      Lifespan Effect
      Decrease
      Genetic Manipulation
      Deletion
      Longevity Category
      Necessary for fitness
      Primary reference

        Homologs in other organisms

        No homologs found

        External links

        Saccharomyces Genome Database
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        Ensembl
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        Entrez Gene
        View on Entrez Gene database (855086)
        Homologues
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        UniProt
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        Internet
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