Caenorhabditis elegansGenAge entry for mpk-1 (Caenorhabditis elegans)

Gene information (ID: 961)

Symbol
mpk-1
Name
MAP Kinase
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
RNA interference of mpk-1 results in a decrease in lifespan.
% change in avg or median lifespan
Mean lifespan is 16% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference
    Observations
    11% mean decrease in lifespan
    % change in avg or median lifespan
    Average lifespan is 11% lower.
    Lifespan Effect
    Decrease
    Genetic Manipulation
    RNA interference
    Longevity Category
    Pro-Longevity
    Primary reference

      In other databases

      GenAge model organism genes
      • A homolog of this gene for Saccharomyces cerevisiae is present as KSS1
      GenAge human genes
      • A homolog of this gene for Homo sapiens is present as MAPK3
      LongevityMap
      • A homolog of this gene for Homo sapiens is present as MAPK3

      Homologs in other organisms

      Danio rerio
      mapk3
      Drosophila melanogaster
      rl
      Homo sapiens
      MAPK3
      Mus musculus
      Mapk3
      Rattus norvegicus
      Mapk3
      Saccharomyces cerevisiae
      KSS1
      Schizosaccharomyces pombe
      spk1

      External links

      WormBase
      Search
      Ensembl
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      Entrez Gene
      View on Entrez Gene database (175545)
      Homologues
      Search HomoloGene
      UniProt
      Search
      Internet
      Search Google or Search Google Scholar