Caenorhabditis elegansGenAge entry for exo-3 (Caenorhabditis elegans)

Gene information (ID: 924)

Symbol
exo-3
Name
EXOnuclease
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
Suppression of exo-3 significantly reduced lifespan: mean lifespan decreased by 20% and maximum lifespan decreased by 10%
% change in max lifespan
Maximum lifespan is 10% lower.
% change in avg or median lifespan
Average lifespan is 20% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as APEX1
    LongevityMap
    • A homolog of this gene for Homo sapiens is present as APEX1

    Homologs in other organisms

    Danio rerio
    apex1
    Homo sapiens
    APEX1
    Mus musculus
    Apex1
    Rattus norvegicus
    Apex1
    Schizosaccharomyces pombe
    apn2

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (173069)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
    Search Google or Search Google Scholar