Drosophila melanogasterGenAge entry for Pten (Drosophila melanogaster)

Gene information (ID: 876)

Symbol
Pten
Aliases
CG5671; Dmel\CG5671; dpten; dPten; dPTEN; DPTEN; pten; PT
Name
CG5671 gene product from transcript CG5671-RB
Organism
Drosophila melanogaster (AnAge)

Potential relevance to longevity and/or ageing

Observations
Lifespan of flies with increased Pten and 4E-BP activity in muscles is extended in comparison with matched controls.
% change in max lifespan
Maximum lifespan is 7.7% higher.
% change in avg or median lifespan
Median lifespan is 12.7% higher.
Lifespan Effect
Increase
Genetic Manipulation
Overexpression
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Mus musculus is present as Pten
    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as PTEN

    Homologs in other organisms

    Danio rerio
    ptena
    Homo sapiens
    PTEN
    Mus musculus
    Pten
    Rattus norvegicus
    Pten

    External links

    FlyBase
    Search
    Ensembl
    Search
    Entrez Gene
    View on Entrez Gene database (43991)
    Homologues
    Search HomoloGene
    UniProt
    Search
    Internet
    Search Google or Search Google Scholar