Drosophila melanogasterGenAge entry for NLaz (Drosophila melanogaster)

Gene information (ID: 872)

Symbol
NLaz
Aliases
BcDNA:RE67583; CG16933; CG33126; CT33980; Dmel\CG33126
Name
Neural Lazarillo
Organism
Drosophila melanogaster (AnAge)

Potential relevance to longevity and/or ageing

Observations
Absence of Nlaz, an homologue of ApoD, leads to reduced lifespan in both sexes compared to wild type flies.
% change in max lifespan
Maximum female lifespan is approximately 12% lower; Maximum male lifespan is approximately 30% lower.
% change in avg or median lifespan
Median female lifespan is 30.8% lower; Median male lifespan is 22.5% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Mutations
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge microarray genes
    • A homolog of this gene for Homo sapiens is present as APOD

    Homologs in other organisms

    Danio rerio
    si:dkey-52k20.7
    Homo sapiens
    APOD
    Mus musculus
    Apod
    Rattus norvegicus
    Apod

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (33324)
    Homologues
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    UniProt
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    Internet
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