Drosophila melanogasterGenAge entry for bsk (Drosophila melanogaster)

Gene information (ID: 837)

Symbol
bsk
Aliases
Bsk; BSK; BSK/DJNK; c-Jun; CG5680; D-JNK; D-junk; DBSK/JN
Name
basket
Organism
Drosophila melanogaster (AnAge)

Potential relevance to longevity and/or ageing

Observations
RNA interference of Bsk in intestinal stem cells, results in mutants with impaired intestinal homeostasis and tissue regeneration and are short-lived.
% change in avg or median lifespan
Average male lifespan is 16.4% lower; Average female lifespan is 10.2% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Caenorhabditis elegans is present as jnk-1
    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as MAPK9

    Homologs in other organisms

    Caenorhabditis elegans
    jnk-1
    Danio rerio
    mapk9
    Homo sapiens
    MAPK9
    Mus musculus
    Mapk8
    Rattus norvegicus
    Mapk9

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (44801)
    Homologues
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    UniProt
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    Internet
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