Mus musculusGenAge entry for Clock (Mus musculus)

Gene information (ID: 814)

Symbol
Clock
Aliases
KAT13D; bHLHe8; mKIAA0334; 5330400M04Rik
Name
Circadian locomotor output cycles kaput
Organism
Mus musculus (AnAge)

Potential relevance to longevity and/or ageing

Observations
Clock-/- mice have a shorten lifespan and develop two age-specific pathologies - cataracts and dermatitis, at a much higher rate than in wild type mice.
% change in max lifespan
Maximum lifespan is more than 20% lower.
% change in avg or median lifespan
Average lifespan is 15% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Deletion
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as CLOCK
    LongevityMap
    • A homolog of this gene for Homo sapiens is present as CLOCK

    Homologs in other organisms

    Danio rerio
    clock
    Homo sapiens
    CLOCK
    Rattus norvegicus
    Clock

    External links

    Mouse Genome Informatics
    Search
    Ensembl
    Search
    Entrez Gene
    View on Entrez Gene database (12753)
    Homologues
    Search HomoloGene
    UniProt
    Search
    Internet
    Search Google or Search Google Scholar