Mus musculusGenAge entry for Zmpste24 (Mus musculus)

Gene information (ID: 789)

Symbol
Zmpste24
Aliases
MADB; FACE1; STE24; Face-1; Ste24p; D030046F19; A530043O
Name
zinc metallopeptidase, STE24 homolog (S. cerevisiae)
Organism
Mus musculus (AnAge)
Known functions and activities
Metalloproteinase involved in the maturation of lamin A (Lmna)

Potential relevance to longevity and/or ageing

Observations
Knockout mice exhibit nuclear architecture abnormalities and signs of accelerated ageing.
Lifespan Effect
Decrease
Genetic Manipulation
Knockout
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as ZMPSTE24

    Homologs in other organisms

    Caenorhabditis elegans
    fce-1
    Danio rerio
    zmpste24
    Drosophila melanogaster
    ste24a
    Homo sapiens
    ZMPSTE24
    Rattus norvegicus
    Zmpste24
    Saccharomyces cerevisiae
    STE24
    Schizosaccharomyces pombe
    SPAC3H1.05

    External links

    Mouse Genome Informatics
    Search
    Ensembl
    Search
    Entrez Gene
    View on Entrez Gene database (230709)
    Homologues
    Search HomoloGene
    UniProt
    Search
    Internet
    Search Google or Search Google Scholar