Drosophila melanogasterGenAge entry for TrxT (Drosophila melanogaster)

Gene information (ID: 686)

Symbol
TrxT
Aliases
3315; CG3315; DmelTrxT; Dmel\CG3315; DmTrxT
Name
Thioredoxin T
Organism
Drosophila melanogaster (AnAge)
Known functions and activities
Thioredoxin T

Potential relevance to longevity and/or ageing

Observations
Overexpression in neurons increased the level of locomotor activity in aged flies and extended the mean lifespan by 15%.
% change in avg or median lifespan
Average lifespan is 15% higher.
Lifespan Effect
Increase
Genetic Manipulation
Overexpression
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Caenorhabditis elegans is present as trx-1
    • A homolog of this gene for Mus musculus is present as Txn1
    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as TXN
    GenDR gene manipulations
    • A homolog of this gene for Caenorhabditis elegans is present as trx-1
    CellAge
    • A homolog of this gene for Homo sapiens is present as TXN

    Homologs in other organisms

    Caenorhabditis elegans
    trx-1
    Danio rerio
    zgc:56493
    Homo sapiens
    TXN
    Mus musculus
    Txn
    Rattus norvegicus
    Txn
    Saccharomyces cerevisiae
    TRX3
    Schizosaccharomyces pombe
    trx2

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (31443)
    Homologues
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    UniProt
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    Internet
    Search Google or Search Google Scholar