Saccharomyces cerevisiaeGenAge entry for SNF1 (Saccharomyces cerevisiae)

Gene information (ID: 619)

Symbol
SNF1
Aliases
CAT1; CCR1; GLC2; HAF3; PAS14
Name
AMP-activated serine/threonine protein kinase
Organism
Saccharomyces cerevisiae (AnAge)

Potential relevance to longevity and/or ageing

Observations
Overexpression shortened lifespan accompanied by signs of premature ageing.
Lifespan Effect
Decrease
Genetic Manipulation
Overexpression
Longevity Category
Anti-Longevity
Primary reference
    Observations
    Replicative lifespan increased by 50% in the alpha strain
    % change in avg or median lifespan
    Replicative lifespan is 50% higher.
    Lifespan Effect
    Increase
    Genetic Manipulation
    Deletion
    Longevity Category
    Anti-Longevity
    Primary reference
      Observations
      Reduced chronological lifespan
      Lifespan Effect
      Decrease
      Genetic Manipulation
      Overexpression
      Longevity Category
      Anti-Longevity
      Primary reference
        Observations
        Mean chronological lifespan decreased in the a strain
        Lifespan Effect
        Decrease
        Genetic Manipulation
        Deletion
        Longevity Category
        Necessary for fitness
        Primary reference

          In other databases

          GenAge model organism genes
          • A homolog of this gene for Drosophila melanogaster is present as SNF1A

          Homologs in other organisms

          Caenorhabditis elegans
          aak-1
          Danio rerio
          prkaa2
          Drosophila melanogaster
          SNF1A
          Homo sapiens
          MARK4
          Mus musculus
          Prkaa1
          Rattus norvegicus
          Prkaa1
          Schizosaccharomyces pombe
          ssp2

          External links

          Saccharomyces Genome Database
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          Ensembl
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          Entrez Gene
          View on Entrez Gene database (852088)
          Homologues
          Search HomoloGene
          UniProt
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          Internet
          Search Google or Search Google Scholar