Drosophila melanogasterGenAge entry for SdhC (Drosophila melanogaster)

Gene information (ID: 594)

Symbol
SdhC
Aliases
BcDNA:RH04289; CG6666; Dmel\CG6666; sdhC
Name
succinate dehydrogenase, cytochrome b556 subunit
Organism
Drosophila melanogaster (AnAge)
Known functions and activities
Succinate dehydrogenase

Potential relevance to longevity and/or ageing

Observations
Mutants expressing a dominant negative form of sdhC in the nervous system had a 22% reduced mean lifespan and signs of oxidative stress induction.
% change in avg or median lifespan
Average lifespan is 22% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Dominant negative mutation
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as SDHC

    Homologs in other organisms

    Danio rerio
    sdhc
    Homo sapiens
    SDHC
    Mus musculus
    Sdhc
    Rattus norvegicus
    Sdhc
    Schizosaccharomyces pombe
    sdh3

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (41340)
    Homologues
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    UniProt
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    Internet
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