Saccharomyces cerevisiaeGenAge entry for RPL31A (Saccharomyces cerevisiae)

Gene information (ID: 562)

Symbol
RPL31A
Aliases
RPL34
Name
ribosomal 60S subunit protein L31A
Organism
Saccharomyces cerevisiae (AnAge)
Known functions and activities
Protein component of the large (60S) ribosomal subunit

Potential relevance to longevity and/or ageing

Observations
Deletion increased mean replicative lifespan by 45%.
% change in avg or median lifespan
Average lifespan is 45% higher.
Lifespan Effect
Increase
Genetic Manipulation
Deletion
Longevity Category
Anti-Longevity
Primary reference
    Observations
    RPL31A and RPL6B were found to increase significantly yeast replicative life span (RLS).
    Lifespan Effect
    Increase
    Genetic Manipulation
    Deletion
    Longevity Category
    Anti-Longevity
    Primary reference
      Observations
      Replicative lifespan increased by 35% in the alpha strain and 50% in a strain
      % change in avg or median lifespan
      Replicative lifespan is 35-50% higher.
      Lifespan Effect
      Increase
      Genetic Manipulation
      Deletion
      Longevity Category
      Anti-Longevity
      Primary reference
        Observations
        Replicative lifespan increased by 35% in the alpha strain and 50% in a strain
        % change in avg or median lifespan
        Replicative lifespan is 35-50% higher.
        Lifespan Effect
        Increase
        Genetic Manipulation
        Deletion
        Longevity Category
        Anti-Longevity
        Primary reference
          Observations
          Mean chronological lifespan decreased in the a strain by more than 50%
          % change in avg or median lifespan
          Mean chronological lifespan is more than 50% lower.
          Lifespan Effect
          Decrease
          Genetic Manipulation
          Deletion
          Longevity Category
          Necessary for fitness
          Primary reference

            In other databases

            GenDR gene manipulations
            • This gene is present as RPL31A

            Homologs in other organisms

            Schizosaccharomyces pombe
            rpl31

            External links

            Saccharomyces Genome Database
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            Ensembl
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            Entrez Gene
            View on Entrez Gene database (851484)
            Homologues
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            UniProt
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            Internet
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