Saccharomyces cerevisiaeGenAge entry for RPD3 (Saccharomyces cerevisiae)

Gene information (ID: 555)

Symbol
RPD3
Aliases
MOF6; REC3; SDI2; SDS6
Name
Histone deacetylase
Organism
Saccharomyces cerevisiae (AnAge)
Known functions and activities
Regulates transcription and silencing

Potential relevance to longevity and/or ageing

Observations
Deletion extended lifespan by 41%, independently of an intact Sir silencing complex.
% change in avg or median lifespan
Lifespan is 41% higher.
Lifespan Effect
Increase
Genetic Manipulation
Deletion
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Drosophila melanogaster is present as Rpd3
    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as HDAC1
    GenDR gene manipulations
    • A homolog of this gene for Drosophila melanogaster is present as Rpd3
    • This gene is present as RPD3
    CellAge
    • A homolog of this gene for Homo sapiens is present as HDAC1

    Homologs in other organisms

    Caenorhabditis elegans
    hda-3
    Danio rerio
    hdac1
    Drosophila melanogaster
    Rpd3
    Homo sapiens
    HDAC1
    Mus musculus
    Gm10093
    Rattus norvegicus
    Hdac1l
    Schizosaccharomyces pombe
    clr6

    External links

    Saccharomyces Genome Database
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (855386)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
    Search Google or Search Google Scholar