Saccharomyces cerevisiaeGenAge entry for RAD50 (Saccharomyces cerevisiae)

Gene information (ID: 532)

Symbol
RAD50
Name
Subunit of MRX complex, with Mre11p and Xrs2p
Organism
Saccharomyces cerevisiae (AnAge)
Known functions and activities
Genomic stability

Potential relevance to longevity and/or ageing

Observations
Mutations result in a 70% reduced lifespan.
% change in avg or median lifespan
Lifespan is 70% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Mutations
Longevity Category
Necessary for fitness
Primary reference

    In other databases

    LongevityMap
    • A homolog of this gene for Homo sapiens is present as RAD50

    Homologs in other organisms

    Caenorhabditis elegans
    rad-50
    Danio rerio
    rad50
    Drosophila melanogaster
    rad50
    Homo sapiens
    RAD50
    Mus musculus
    Rad50
    Rattus norvegicus
    Rad50
    Schizosaccharomyces pombe
    rad50

    External links

    Saccharomyces Genome Database
    Search
    Ensembl
    Search
    Entrez Gene
    View on Entrez Gene database (855471)
    Homologues
    Search HomoloGene
    UniProt
    Search
    Internet
    Search Google or Search Google Scholar