Caenorhabditis elegansGenAge entry for rab-7 (Caenorhabditis elegans)

Gene information (ID: 530)

Symbol
rab-7
Name
RAB family
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Rab GTPase

Potential relevance to longevity and/or ageing

Observations
RNA interference decreased median lifespan by 32% in wild type animals, 48% in a daf-2 background and 18% in daf-2/daf-16 double mutants.
% change in avg or median lifespan
Median lifespan is 32% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Saccharomyces cerevisiae is present as YPT7
    GenDR gene manipulations
    • A homolog of this gene for Saccharomyces cerevisiae is present as YPT7

    Homologs in other organisms

    Danio rerio
    rab7
    Drosophila melanogaster
    Rab7
    Homo sapiens
    RAB7A
    Mus musculus
    Rab7a
    Rattus norvegicus
    Rab7a
    Saccharomyces cerevisiae
    YPT7
    Schizosaccharomyces pombe
    ypt7

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (174834)
    Homologues
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    UniProt
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    Internet
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