Mus musculusGenAge entry for Pck1 (Mus musculus)

Gene information (ID: 497)

Symbol
Pck1
Aliases
PEPCK; Pck-1; AI265463
Name
phosphoenolpyruvate carboxykinase 1, cytosolic
Organism
Mus musculus (AnAge)

Potential relevance to longevity and/or ageing

Observations
Overexpression in skeletal muscle results in an increased number of mitochondria and extended lifespan. Transgenic mice ate 60% more than controls but had half the body weight and 10% of the body fat.
Lifespan Effect
Increase
Genetic Manipulation
Overexpression
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as PCK1
    GenDR gene manipulations
    • This gene is present as Pck1

    Homologs in other organisms

    Caenorhabditis elegans
    pck-1
    Danio rerio
    pck1
    Drosophila melanogaster
    Pepck
    Homo sapiens
    PCK1
    Rattus norvegicus
    Pck1

    External links

    Mouse Genome Informatics
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (18534)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
    Search Google or Search Google Scholar