Drosophila melanogasterGenAge entry for mys (Drosophila melanogaster)

Gene information (ID: 451)

Symbol
mys
Aliases
beta-int; beta-Int; beta-integrin; beta-PS; beta1; beta
Name
myospheroid
Organism
Drosophila melanogaster (AnAge)
Known functions and activities
Beta integrin

Potential relevance to longevity and/or ageing

Observations
Heterozygous MYS (beta-integrin) female mutants display extended median and maximum lifespan.
% change in avg or median lifespan
Female median lifespan is 44-95% higher.
Lifespan Effect
Increase
Genetic Manipulation
Mutation
Longevity Category
Anti-Longevity
Primary reference
    Observations
    Mutants exhibit ameliorated age-related declines in locomotor activity and an increase in mean lifespan of 20%.
    % change in avg or median lifespan
    Average female lifespan is 20% higher.
    Lifespan Effect
    Increase
    Genetic Manipulation
    Mutation
    Longevity Category
    Anti-Longevity
    Primary reference

      In other databases

      GenAge model organism genes
      • A homolog of this gene for Caenorhabditis elegans is present as pat-3
      LongevityMap
      • A homolog of this gene for Homo sapiens is present as ITGB3

      Homologs in other organisms

      Caenorhabditis elegans
      pat-3
      Danio rerio
      itgb3b
      Homo sapiens
      ITGB3
      Mus musculus
      Itgb3
      Rattus norvegicus
      Itgb2

      External links

      FlyBase
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      Ensembl
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      Entrez Gene
      View on Entrez Gene database (44885)
      Homologues
      Search HomoloGene
      UniProt
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      Internet
      Search Google or Search Google Scholar