Mus musculusGenAge entry for Msra (Mus musculus)

Gene information (ID: 446)

Symbol
Msra
Aliases
MSR-A; 2310045J23Rik; 6530413P12Rik
Name
Methionine sulfoxide reductase A
Organism
Mus musculus (AnAge)
Known functions and activities
MSRA repairs damage resulting from oxidative stress

Potential relevance to longevity and/or ageing

Observations
Knockouts exhibit a shorter lifespan and enhanced sensitivity to oxidative stress.
Lifespan Effect
Decrease
Genetic Manipulation
Knockout
Longevity Category
Pro-Longevity
Primary reference
    Observations
    No effect on aging, as determined by lifespan.
    Lifespan Effect
    Not Recorded
    Genetic Manipulation
    Mutations
    Primary reference

      In other databases

      GenAge model organism genes
      • A homolog of this gene for Drosophila melanogaster is present as Eip71CD
      • A homolog of this gene for Saccharomyces cerevisiae is present as MXR1
      GenAge human genes
      • A homolog of this gene for Homo sapiens is present as MSRA

      Homologs in other organisms

      Caenorhabditis elegans
      msra-1
      Danio rerio
      si:dkey-221h15.1
      Drosophila melanogaster
      Eip71CD
      Homo sapiens
      MSRA
      Rattus norvegicus
      Msra
      Saccharomyces cerevisiae
      MXR1
      Schizosaccharomyces pombe
      mxr1

      External links

      Mouse Genome Informatics
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      Ensembl
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      Entrez Gene
      View on Entrez Gene database (110265)
      Homologues
      Search HomoloGene
      UniProt
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      Internet
      Search Google or Search Google Scholar