Caenorhabditis elegansGenAge entry for mep-1 (Caenorhabditis elegans)

Gene information (ID: 431)

Symbol
mep-1
Name
Mog interacting, Ectopic P granules
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Post-transcriptional gene regulation

Potential relevance to longevity and/or ageing

Observations
RNA interference results in a 39% decrease in median lifespan in daf-2 mutants, 14% decrease in lifespan in daf-2/daf-16 double mutants and 8% decrease in median lifespan in a wild-type background.
% change in avg or median lifespan
Median lifespan is 8% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    LongevityMap
    • A homolog of this gene for Homo sapiens is present as ZFAT

    Homologs in other organisms

    Drosophila melanogaster
    MEP-1
    Homo sapiens
    ZFAT

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (178074)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
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