Saccharomyces cerevisiaeGenAge entry for MEC1 (Saccharomyces cerevisiae)

Gene information (ID: 430)

Symbol
MEC1
Aliases
ESR1; RAD31; SAD3
Name
Mec1p
Organism
Saccharomyces cerevisiae (AnAge)
Known functions and activities
Involved in replication stress and DNA damage

Potential relevance to longevity and/or ageing

Observations
Mutants have a 3-fold reduced mean and maximum chronological lifespan under conditions of medium depletion.
% change in avg or median lifespan
Lifespan is three-fold lower.
Lifespan Effect
Decrease
Genetic Manipulation
Mutation
Longevity Category
Necessary for fitness
Primary reference

    In other databases

    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as ATR
    LongevityMap
    • A homolog of this gene for Homo sapiens is present as ATR

    Homologs in other organisms

    Danio rerio
    atr
    Drosophila melanogaster
    mei-41
    Homo sapiens
    ATR
    Mus musculus
    Atr
    Rattus norvegicus
    Atr
    Schizosaccharomyces pombe
    rad3

    External links

    Saccharomyces Genome Database
    Search
    Ensembl
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    Entrez Gene
    View on Entrez Gene database (852433)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
    Search Google or Search Google Scholar