Caenorhabditis elegansGenAge entry for let-60 (Caenorhabditis elegans)

Gene information (ID: 407)

Symbol
let-60
Name
LEThal
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Ras homolog

Potential relevance to longevity and/or ageing

Observations
Activating mutations weakly suppress constitutive dauer diapause in daf-2 and age-1 mutants and extend lifespan induced by mutation of daf-2.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Saccharomyces cerevisiae is present as RAS2

    Homologs in other organisms

    Danio rerio
    nras
    Drosophila melanogaster
    Ras85D
    Homo sapiens
    NRAS
    Mus musculus
    Kras
    Rattus norvegicus
    Nras
    Saccharomyces cerevisiae
    RAS2
    Schizosaccharomyces pombe
    ras1

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (178104)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
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