Caenorhabditis elegansGenAge entry for jnk-1 (Caenorhabditis elegans)

Gene information (ID: 381)

Symbol
jnk-1
Name
Jun N-terminal Kinase
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Signal transduction

Potential relevance to longevity and/or ageing

Observations
Overexpression increases lifespan by 40%.
% change in avg or median lifespan
Lifespan is 40% higher.
Lifespan Effect
Increase
Genetic Manipulation
Overexpression
Longevity Category
Pro-Longevity
Primary reference
    Observations
    Mutant worms have a 30% shortened maximal lifespan.
    % change in max lifespan
    Maximum lifespan is 30% lower.
    Lifespan Effect
    Decrease
    Genetic Manipulation
    Mutation
    Longevity Category
    Pro-Longevity
    Primary reference

      In other databases

      GenAge model organism genes
      • A homolog of this gene for Drosophila melanogaster is present as bsk
      GenAge human genes
      • A homolog of this gene for Homo sapiens is present as MAPK9

      Homologs in other organisms

      Danio rerio
      mapk9
      Drosophila melanogaster
      bsk
      Homo sapiens
      MAPK9
      Mus musculus
      Mapk8
      Rattus norvegicus
      Mapk9

      External links

      WormBase
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      Ensembl
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      Entrez Gene
      View on Entrez Gene database (177460)
      Homologues
      Search HomoloGene
      UniProt
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      Internet
      Search Google or Search Google Scholar