Saccharomyces cerevisiaeGenAge entry for HXK2 (Saccharomyces cerevisiae)

Gene information (ID: 357)

Symbol
HXK2
Aliases
HEX1; HKB; SCI2
Name
hexokinase 2
Organism
Saccharomyces cerevisiae (AnAge)
Known functions and activities
Catalyzes the addition of phosphate to glucose to make glucose-6-phosphate

Potential relevance to longevity and/or ageing

Observations
Deletion extends lifespan about 50%.
% change in avg or median lifespan
Lifespan is about 50% higher.
Lifespan Effect
Increase
Genetic Manipulation
Deletion
Longevity Category
Anti-Longevity
Primary reference
    Observations
    Mean chronological lifespan strongly increased in the a strain
    Lifespan Effect
    Increase
    Genetic Manipulation
    Deletion
    Longevity Category
    Anti-Longevity
    Primary reference

      In other databases

      GenDR gene manipulations
      • This gene is present as HXK2

      Homologs in other organisms

      Caenorhabditis elegans
      CELE_Y77E11A.1
      Drosophila melanogaster
      Hex-t1
      Homo sapiens
      GCK
      Mus musculus
      Hk3
      Rattus norvegicus
      LOC100364027

      External links

      Saccharomyces Genome Database
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      Ensembl
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      Entrez Gene
      View on Entrez Gene database (852639)
      Homologues
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      UniProt
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      Internet
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