GenAge entry for HAP4 (Saccharomyces cerevisiae)
Gene information (ID: 332)
- Symbol
- HAP4
- Name
- Hap4p
- Organism
- Saccharomyces cerevisiae (AnAge)
- Known functions and activities
- Transcription factor required for the metabolic shift from fermentation to respiration
Potential relevance to longevity and/or ageing
- Observations
- Overexpression extends lifespan about 40% under growth conditions favoring fermentation.
- % change in avg or median lifespan
- Lifespan is about 40% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Overexpression
- Longevity Category
- Pro-Longevity
- Primary reference
-
- Observations
- Mean chronological lifespan decreased in the a strain
- Lifespan Effect
- Decrease
- Genetic Manipulation
- Deletion
- Longevity Category
- Necessary for fitness
- Primary reference
-
In other databases
- GenDR gene manipulations
- This gene is present as HAP4
Homologs in other organisms
No homologs found
External links
- Saccharomyces Genome Database
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (853751)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar