Mus musculusGenAge entry for Gpx4 (Mus musculus)

Gene information (ID: 324)

Symbol
Gpx4
Aliases
PHGPx; snGPx; mtPHGPx; 1700027O09Rik
Name
Glutathione peroxidase 4
Organism
Mus musculus (AnAge)
Known functions and activities
Detoxification of oxidative damage to membrane lipids

Potential relevance to longevity and/or ageing

Observations
Heterozygous knockouts have a 7% increase in median lifespan.
% change in avg or median lifespan
Median lifespan is 7% higher.
Lifespan Effect
Increase
Genetic Manipulation
Knockout
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as GPX4
    LongevityMap
    • A homolog of this gene for Homo sapiens is present as GPX4

    Homologs in other organisms

    Caenorhabditis elegans
    R05H10.5
    Drosophila melanogaster
    PHGPx
    Homo sapiens
    GPX4
    Rattus norvegicus
    Gpx4
    Schizosaccharomyces pombe
    gpx1

    External links

    Mouse Genome Informatics
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (625249)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
    Search Google or Search Google Scholar