Caenorhabditis elegansGenAge entry for let-363 (Caenorhabditis elegans)

Gene information (ID: 32)

Symbol
let-363
Name
LEThal
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Regulation of cell growth and differentiation in response to nutrients

Potential relevance to longevity and/or ageing

Observations
RNA interference extends lifespan by about 150%.
% change in avg or median lifespan
Lifespan is 150% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Drosophila melanogaster is present as Tor
    • A homolog of this gene for Saccharomyces cerevisiae is present as TOR1
    • A homolog of this gene for Mus musculus is present as Mtor
    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as MTOR
    GenDR gene manipulations
    • This gene is present as let-363
    • A homolog of this gene for Saccharomyces cerevisiae is present as TOR1
    LongevityMap
    • A homolog of this gene for Homo sapiens is present as MTOR

    Homologs in other organisms

    Danio rerio
    mtor
    Drosophila melanogaster
    Tor
    Homo sapiens
    MTOR
    Mus musculus
    Mtor
    Rattus norvegicus
    Mtor
    Saccharomyces cerevisiae
    TOR1
    Schizosaccharomyces pombe
    tor1

    External links

    WormBase
    Search
    Ensembl
    Search
    Entrez Gene
    View on Entrez Gene database (172167)
    Homologues
    Search HomoloGene
    UniProt
    Search
    Internet
    Search Google or Search Google Scholar