Saccharomyces cerevisiaeGenAge entry for GPA2 (Saccharomyces cerevisiae)

Gene information (ID: 319)

Symbol
GPA2
Aliases
SSP101
Name
Gpa2p
Organism
Saccharomyces cerevisiae (AnAge)
Known functions and activities
Encodes G-protein alpha subunit, which acts in parallel to Ras pathway to activate adenylate cyclase

Potential relevance to longevity and/or ageing

Observations
Deletion increases lifespan by about 50%.
% change in avg or median lifespan
Lifespan is about 50% higher.
Lifespan Effect
Increase
Genetic Manipulation
Deletion
Longevity Category
Anti-Longevity
Primary reference
    Observations
    Mean chronological lifespan decreased in the a strain
    Lifespan Effect
    Decrease
    Genetic Manipulation
    Deletion
    Longevity Category
    Necessary for fitness
    Primary reference

      In other databases

      GenDR gene manipulations
      • This gene is present as GPA2
      • A homolog of this gene for Schizosaccharomyces pombe is present as gpa2

      Homologs in other organisms

      Schizosaccharomyces pombe
      gpa2

      External links

      Saccharomyces Genome Database
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      Ensembl
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      Entrez Gene
      View on Entrez Gene database (856741)
      Homologues
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      UniProt
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      Internet
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