Saccharomyces cerevisiaeGenAge entry for ATP2 (Saccharomyces cerevisiae)

Gene information (ID: 29)

Symbol
ATP2
Name
ATP synthase F1 subunit gamma
Organism
Saccharomyces cerevisiae (AnAge)
Known functions and activities
ATP synthase subunit

Potential relevance to longevity and/or ageing

Observations
A mutation causes a clonal senescence phenotype resulting from the disruption of the age asymmetry between mother and daughter cells in that that daughter cells are born old.
Lifespan Effect
Decrease
Genetic Manipulation
Mutation
Longevity Category
Pro-Longevity
Primary reference
    Observations
    Replicative lifespan decreased by 50% in the alpha strain
    % change in avg or median lifespan
    Replicative lifespan is 50% lower.
    Lifespan Effect
    Decrease
    Genetic Manipulation
    Deletion
    Longevity Category
    Necessary for fitness
    Primary reference

      In other databases

      GenAge model organism genes
      • A homolog of this gene for Caenorhabditis elegans is present as atp-2

      Homologs in other organisms

      Caenorhabditis elegans
      atp-2
      Danio rerio
      zgc:163069
      Drosophila melanogaster
      ATPsyn-beta
      Homo sapiens
      ATP5B
      Mus musculus
      Atp5b
      Rattus norvegicus
      Atp5b
      Schizosaccharomyces pombe
      atp2

      External links

      Saccharomyces Genome Database
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      Ensembl
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      Entrez Gene
      View on Entrez Gene database (853585)
      Homologues
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      UniProt
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      Internet
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