Saccharomyces cerevisiaeGenAge entry for FBP1 (Saccharomyces cerevisiae)

Gene information (ID: 280)

Symbol
FBP1
Aliases
ACN8
Name
Fructose-1,6-bisphosphatase, key regulatory enzyme in the gluconeogenesis pathway, required for gluc
Organism
Saccharomyces cerevisiae (AnAge)
Known functions and activities
Glucose metabolism

Potential relevance to longevity and/or ageing

Observations
Deletion did increase survival during the first 15 days during chronological ageing, but did not increase chronological lifespan. Deletion reduced production of reactive oxygen species while overexpression shortened lifespan.
Lifespan Effect
Decrease
Genetic Manipulation
Overexpression
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Caenorhabditis elegans is present as fbp-1

    Homologs in other organisms

    Caenorhabditis elegans
    fbp-1
    Danio rerio
    fbp2
    Drosophila melanogaster
    fbp
    Homo sapiens
    FBP2
    Mus musculus
    Fbp1
    Rattus norvegicus
    Fbp2
    Schizosaccharomyces pombe
    fbp1

    External links

    Saccharomyces Genome Database
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (851092)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
    Search Google or Search Google Scholar