Mus musculusGenAge entry for Ercc2 (Mus musculus)

Gene information (ID: 222)

Symbol
Ercc2
Aliases
XPD; CXPD; Ercc-2; AA407812; AU020867; AW240756
Name
Excision repair cross-complementing rodent repair deficiency, complementation group 2
Organism
Mus musculus (AnAge)
Known functions and activities
Helicase involved in DNA repair and condensation

Potential relevance to longevity and/or ageing

Observations
Mutations increase cancer incidence and appear to accelerate ageing.
Lifespan Effect
Decrease
Genetic Manipulation
Mutations
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as ERCC2
    LongevityMap
    • A homolog of this gene for Homo sapiens is present as ERCC2

    Homologs in other organisms

    Caenorhabditis elegans
    CELE_Y50D7A.2
    Danio rerio
    ercc2
    Drosophila melanogaster
    Xpd
    Homo sapiens
    ERCC2
    Rattus norvegicus
    Ercc2
    Saccharomyces cerevisiae
    RAD3
    Schizosaccharomyces pombe
    rad15

    External links

    Mouse Genome Informatics
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (13871)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
    Search Google or Search Google Scholar