Mus musculusGenAge entry for SOD3 (Mus musculus)

Gene information (ID: 2163)

Symbol
SOD3
Name
superoxide dismutase 3
Organism
Mus musculus (AnAge)

Potential relevance to longevity and/or ageing

Observations
Mice overexpressing a mutant variant of human SOD3 (R213G) had a shortened lifespan (11 months). Mice expressing the SOD3 transgene (SOD3-Tg) displayed features of accelerated ageing such as hair greying and abnormal gait. The mice also had systemic inflammation and organ degeneration.
Lifespan Effect
Decrease
Genetic Manipulation
Mutation
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    LongevityMap
    • A homolog of this gene for Homo sapiens is present as SOD3

    Homologs in other organisms

    Homo sapiens
    SOD3
    Homo sapiens
    SOD3
    Homo sapiens
    SOD3

    External links

    Mouse Genome Informatics
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (6649)
    Homologues
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    UniProt
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    Internet
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