Drosophila melanogasterGenAge entry for ATPCL (Drosophila melanogaster)

Gene information (ID: 2105)

Symbol
ATPCL
Name
ATP citrate lyase
Organism
Drosophila melanogaster (AnAge)

Potential relevance to longevity and/or ageing

Observations
Reduced ATPCL activity extended male fly lifepsan by 32%.
% change in avg or median lifespan
Median lifespan is 32% higher.
Lifespan Effect
Increase
Genetic Manipulation
Mutation
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenDR gene expression
    • A homolog of this gene for Mus musculus is present as Acly
    CellAge
    • A homolog of this gene for Homo sapiens is present as ACLY

    Homologs in other organisms

    Caenorhabditis elegans
    D1005.1
    Danio rerio
    uncharacterized_F1R5
    Homo sapiens
    ACLY
    Mus musculus
    Acly
    Rattus norvegicus
    Acly
    Schizosaccharomyces pombe
    SPBC1703.07

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (36760)
    Homologues
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    UniProt
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    Internet
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